Nam Chu
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
36
Citations
667
Est. group size
~2
Recurring co-author estimate
Active years
19
Publishing since 2008
Nam Chu's research focuses on the protein kinase Akt, a key signaling protein involved in cell growth and cancer, studying how it is activated, regulated, and modified using techniques like protein semisynthesis (chemically building proteins with precise modifications) and structural biology. The work also extends into related areas such as mTOR signaling, prion protein diseases, neurodegeneration models, and small-molecule cancer therapies.
Publication output has fluctuated over the past decade, rising to a peak around 2020 and 2022, dipping in 2023-2024, and increasing again in 2025-2026, with an average of about 2 papers per year over the last five years.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Structural and mechanistic basis of mTORC2 activation of protein kinase AKT/PKB
Biochemical Journal · 2026
- Chemoselective Semisynthesis of Covalent Nanobody-Guided Protein Degraders in Neurons
Research Square · 2026
- Abstract 3906: Small-molecule inhibitors as salvage therapy for CBFB::MYH11-associated acute myeloid leukemia.
Cancer Research · 2026
- Structural basis for the recruitment and selective phosphorylation of Akt by mTORC2
Science · 2025
- Prion protein pathology in Ubiquilin 2 models of ALS
Neurobiology of Disease · 2024
- Analyzing protein posttranslational modifications using enzyme-catalyzed expressed protein ligation
Methods in enzymology on CD-ROM/Methods in enzymology · 2023
- PH domain-mediated autoinhibition and oncogenic activation of Akt
eLife · 2022
- Utilizing a Baculovirus/Insect Cell Expression System and Expressed Protein Ligation (EPL) for Protein Semisynthesis
Current Protocols · 2022
- PH Domain-Mediated Autoinhibition and Oncogenic Activation of Akt
bioRxiv (Cold Spring Harbor Laboratory) · 2022
- Author response: PH domain-mediated autoinhibition and oncogenic activation of Akt
2022
- Multifaceted Regulation of Akt by Diverse C-Terminal Post-translational Modifications
ACS Chemical Biology · 2021
- Protein Semisynthesis
2021
- The structural determinants of PH domain-mediated regulation of Akt revealed by segmental labeling
eLife · 2020
- The protein kinase Akt acts as a coat adaptor in endocytic recycling
Nature Cell Biology · 2020
- Elucidation of remdesivir cytotoxicity pathways through genome-wide CRISPR-Cas9 screening and transcriptomics
bioRxiv (Cold Spring Harbor Laboratory) · 2020
- bioRxiv (Cold Spring Harbor Laboratory)×3
- eLife×2
- The FASEB Journal×2
- Cell×1
- Science×1
- Darien E. Reed
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Jinmin Miao
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Frederick Nguele Meke
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Cho-Hao Lin
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Harrison J. McNabb
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
Claim or correct this profile