LabCompass

Frederick Nguele Meke

Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette

Early career · publishing since 2020Rising activity

Publications

43

Citations

202

Est. group size

~10

Recurring co-author estimate

Active years

7

Publishing since 2020

Research summary
AI-generated

Frederick Nguele Meke's research focuses on how certain enzymes called phosphatases (proteins that remove phosphate groups from other proteins) control cancer-related signaling pathways, particularly in blood cancers like leukemia and lymphoma. Recent work examines proteins such as PRL2 and SHP2, studying how blocking their activity affects tumor growth and other cellular processes like protein breakdown (autophagy). The lab also uses advanced imaging and mass spectrometry techniques to study protein forms within tissue samples.

Cancer cell signaling (PI3K/AKT/mTOR, SHP2 pathways)Protein tyrosine phosphatases in diseaseLeukemia and lymphoma biologyPTEN protein regulation and tumor suppressionMass spectrometry imaging of proteins

Publication output was minimal or absent for most of the past decade but increased sharply starting in 2022, with a pronounced spike in 2024, suggesting a recent period of growing research activity.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 8.4/year recently
1718192020: 1 publication20212022: 2 publications222023: 4 publications232024: 32 publications32242025: 3 publications252026: 1 publication26
Publishes in
  • Cancer Research×2
  • Analytical Chemistry×1
  • Proceedings of the National Academy of Sciences×1
  • Blood×1
  • Autophagy×1
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This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 20, 2026.

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