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Jinmin Miao

Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette

OpenAlex ORCID
Established · publishing since 1990Rising activity
PI3K/AKT/mTOR signaling in cancerProtein Tyrosine PhosphatasesGalectins and Cancer BiologyProtein Kinase Regulation and GTPase SignalingChronic Myeloid Leukemia Treatments

Publications

64

Citations

1,564

Est. group size

~10

Recurring co-author estimate

Active years

37

Publishing since 1990

Research summary
AI-generated

Jinmin Miao's research focuses on protein tyrosine phosphatases (enzymes that remove phosphate groups from proteins, a key step in cell signaling) and their role in cancer, particularly SHP1, SHP2, and PTPN22. Work spans drug discovery approaches like targeted protein degradation and small-molecule inhibitors, studying how these enzymes affect processes such as tumor growth, immune cell infiltration, blood cell development, and cancer drug resistance. Studies use mouse models, structural biology, and cell-based assays to understand and target KRAS-related and phosphatase-driven signaling pathways in cancers including breast, pancreatic, colorectal, and ovarian cancer.

Protein tyrosine phosphatases (SHP1, SHP2, PTPN22)Cancer drug discovery and targeted protein degradationKRAS signaling and GTPase regulationTumor immunology and immune cell infiltrationCancer metastasis and drug resistance

Publication output was low and sporadic from 2017-2021, then increased notably from 2022-2023, with a sharp spike in 2024 before dropping again in 2025-2026.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 9.6/year recently
17182019: 1 publication192020: 2 publications202021: 1 publication212022: 4 publications222023: 5 publications232024: 36 publications36242025: 2 publications252026: 1 publication26
Recent publications
Publishes in
  • Nature Communications×2
  • Cancer Research Communications×2
  • Neuron×1
  • Oncogene×1
  • Angewandte Chemie International Edition×1
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This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 20, 2026.

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