Harrison J. McNabb
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
Publications
12
Citations
531
Est. group size
—
Recurring co-author estimate
Active years
6
Publishing since 2020
Harrison J. McNabb studies how cells control G protein signaling, a common way that cells receive and respond to signals from hormones and drugs. His work focuses specifically on a protein called RGS2 and how it is recognized and broken down by another protein, FBXO44, including efforts to find small molecules that block this interaction as potential research tools or drug leads.
Publication output has been modest and uneven over the last decade, with no output before 2020 and a recent uptick in 2025 following a quieter 2022 and 2024.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Discovery of RGS2-FBXO44 interaction inhibitors using a cell-based NanoBit assay
Molecular Pharmacology · 2025
- Gβ5 Interactome Is Enriched with Proteins Associated with Neuronal Development and Aging in Neuro-2A Cells Determined via miniTurbo Proximity Labeling and Mass Spectrometry (Abstract ID: 159174)
Journal of Pharmacology and Experimental Therapeutics · 2025
- Systematic analysis of the RGS2 degron reveals characteristics of substrate recognition by the F-box protein FBXO44
Journal of Biological Chemistry · 2025
- Regulators of G protein Signaling (RGS) proteins in GtoPdb v.2025.3
IUPHAR/BPS Guide to Pharmacology CITE · 2025
- Determining molecular characteristics of the RGS2-FBXO44 interaction – A multipronged approach
Journal of Pharmacology and Experimental Therapeutics · 2024
- The Concise Guide to PHARMACOLOGY 2023/24: Introduction and Other Protein Targets
British Journal of Pharmacology · 2023
- Discovery and Validation of RGS2-FBXO44 Protein-Protein Interaction Inhibitors
Journal of Pharmacology and Experimental Therapeutics · 2023
- THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Introduction and Other Protein Targets
British Journal of Pharmacology · 2021
- Regulators of G protein Signaling (RGS) proteins in GtoPdb v.2021.2
IUPHAR/BPS Guide to Pharmacology CITE · 2021
- Emerging Roles for Regulator of G Protein Signaling 2 in (Patho)physiology
Molecular Pharmacology · 2020
- N-Terminal Targeting of Regulator of G Protein Signaling Protein 2 for F-Box Only Protein 44–Mediated Proteasomal Degradation
Molecular Pharmacology · 2020
- N‐Terminal Targeting of RGS2 for FBXO44‐Mediated Proteasomal Degradation
The FASEB Journal · 2020
- Molecular Pharmacology×3
- Journal of Pharmacology and Experimental Therapeutics×3
- British Journal of Pharmacology×2
- IUPHAR/BPS Guide to Pharmacology CITE×2
- The FASEB Journal×1
- Jonathan M. Spehar
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Chun-Liang Chen
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Andrew Rust
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Angeline M. Lyon
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Darien E. Reed
Biochemistry, Genetics and Molecular Biology · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 20, 2026.
Claim or correct this profile