LabCompass

Angeline M. Lyon

Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette

OpenAlex ORCID
Mid career · publishing since 2007
Protein Kinase Regulation and GTPase SignalingReceptor Mechanisms and SignalingCellular transport and secretionMitochondrial Function and PathologyCell death mechanisms and regulation

Publications

77

Citations

750

Est. group size

~9

Recurring co-author estimate

Active years

20

Publishing since 2007

Research summary
AI-generated

Angeline M. Lyon's research focuses on how cells transmit chemical signals through enzymes called phospholipases (PLC), which cut lipid molecules in cell membranes to generate secondary messenger signals inside cells. Her lab studies the molecular structures of these enzymes and how they are switched on and off by G-proteins (molecular switches involved in many hormone and neurotransmitter responses), with implications for understanding cell signaling pathways relevant to conditions like immune activation.

Phospholipase C structure and regulationG-protein signalingCell membrane biochemistryEnzyme activation mechanismsStructural biology of signaling proteins

Publication output has fluctuated over the last decade, dipping around 2021-2024 before rising again in 2025-2026, suggesting an overall active but variable publication cadence.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 5.4/year recently
2017: 7 publications172018: 9 publications9182019: 9 publications9192020: 5 publications202021: 3 publications212022: 4 publications222023: 5 publications232024: 2 publications242025: 7 publications252026: 9 publications926
Recent publications
Publishes in
  • The FASEB Journal×21
  • Journal of Biological Chemistry×7
  • Journal of Pharmacology and Experimental Therapeutics×7
  • bioRxiv (Cold Spring Harbor Laboratory)×4
  • Communications Biology×3
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By research-topic overlap
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  • Chun-Liang Chen

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  • Sadikshya Aryal

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This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 20, 2026.

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