Austin T. Raper
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
14
Citations
462
Est. group size
—
Recurring co-author estimate
Active years
9
Publishing since 2016
Austin T. Raper studies the molecular machinery cells use to copy, repair, and edit DNA, with a particular focus on how the CRISPR/Cas9 gene-editing system and DNA-repair enzymes work at a mechanistic level. This work uses biochemical and biophysical techniques, including single-molecule fluorescence and structural methods, to understand how these proteins move and function while interacting with DNA. The research is relevant to students interested in gene-editing tools, DNA repair, and the biophysics of enzyme-DNA interactions.
Publication output peaked around 2018 and has since slowed considerably, with sparse and irregular output (often zero) in recent years.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Conformational transitions of Streptococcus pyogenes Cas9 induced by salt and single-guide RNA binding
Journal of Biological Chemistry · 2024
- Dynamic Processing of a Common Oxidative DNA Lesion by the First Two Enzymes of the Base Excision Repair Pathway
Journal of Molecular Biology · 2021
- Identification and investigation of a novel function of the RuvC nuclease of CRISPR/Cas9
2020
- Identification and investigation of a novel function of the RuvC nuclease of CRISPR/Cas9
2020
- Functional Insights Revealed by the Kinetic Mechanism of CRISPR/Cas9
Journal of the American Chemical Society · 2018
- Kinetic Mechanism of DNA Polymerases: Contributions of Conformational Dynamics and a Third Divalent Metal Ion
Chemical Reviews · 2018
- Bidirectional Degradation of DNA Cleavage Products Catalyzed by CRISPR/Cas9
Journal of the American Chemical Society · 2018
- Investigation of sliding DNA clamp dynamics by single-molecule fluorescence, mass spectrometry and structure-based modeling
Nucleic Acids Research · 2018
- Sharpening the Scissors: Mechanistic Details of CRISPR/Cas9 Improve Functional Understanding and Inspire Future Research
Journal of the American Chemical Society · 2018
- Structural basis for the D-stereoselectivity of human DNA polymerase β
Nucleic Acids Research · 2017
- Structural Insights into the Post-Chemistry Steps of Nucleotide Incorporation Catalyzed by a DNA Polymerase
Journal of the American Chemical Society · 2016
- Single-Molecule Investigation of Response to Oxidative DNA Damage by a Y-Family DNA Polymerase
Biochemistry · 2016
- Investigation of Intradomain Motions of a Y-Family DNA Polymerase during Substrate Binding and Catalysis
Biochemistry · 2016
- Advances in Structural and Single-Molecule Methods for Investigating DNA Lesion Bypass and Repair Polymerases
Chemical Research in Toxicology · 2016
- Journal of the American Chemical Society×4
- Nucleic Acids Research×2
- Biochemistry×2
- Chemical Reviews×1
- Journal of Molecular Biology×1
- Millie M. Georgiadis
Biochemistry, Genetics and Molecular Biology · Indiana University
- Aki Inase
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- A. Richard Morgan
Biochemistry, Genetics and Molecular Biology · Indiana University
- Ioulia Rouzina
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Buket Onel
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
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