LabCompass

Millie M. Georgiadis

Biochemistry, Genetics and Molecular Biology · Indiana University

OpenAlex ORCID
DNA and Nucleic Acid ChemistryDNA Repair MechanismsHIV/AIDS drug development and treatmentAdvanced biosensing and bioanalysis techniquesHIV Research and Treatment

Publications

170

Citations

4,451

Est. group size

—

Recurring co-author estimate

Active years

38

Publishing since 1989

Research summary
AI-generated

Millie M. Georgiadis studies the three-dimensional structures of DNA and the enzymes that copy and repair it, using techniques like X-ray crystallography and cryo-electron microscopy to see how these molecules interact at atomic detail. A major thread is engineering expanded genetic systems (synthetic DNA with extra 'letters') and understanding how DNA polymerases can be evolved to work with them. The work also extends to drug discovery, particularly finding small molecules that target DNA-repair enzymes as potential cancer therapies.

Structural biology of DNA and DNA-binding moleculesDNA polymerases and enzyme engineeringExpanded/synthetic genetic systems (e.g., Hachimoji DNA)DNA repair enzymes (APE1) as drug targetsStructure- and fragment-based drug discovery

Publication activity has been steady with year-to-year fluctuation and an uptick in the most recent years, averaging about 8 papers per year over the last five years.

Generated by claude-opus-4-8 from public bibliographic data · Jul 11, 2026

Publication cadence
Publications per year over the last 10 years — averaging 8.4/year recently
2017: 10 publications172018: 4 publications182019: 6 publications192020: 5 publications202021: 5 publications212022: 8 publications222023: 9 publications232024: 2 publications242025: 7 publications252026: 16 publications1626
Recent publications
Publishes in
  • Figshare×15
  • Journal of Biological Chemistry×6
  • PMC×4
  • SSRN Electronic Journal×3
  • Journal of the American Chemical Society×2

This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 11, 2026.

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