Ioulia Rouzina
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
241
Citations
7,438
Est. group size
~3
Recurring co-author estimate
Active years
31
Publishing since 1996
Ioulia Rouzina studies how DNA and proteins physically interact, using single-molecule biophysical tools like optical tweezers to measure forces and binding behaviors. Her work spans topics such as how viruses like HIV package and unpack their genetic material, how DNA-binding proteins (including drugs and metal complexes) attach to and reshape DNA, and how proteins that package DNA into chromosomes (nucleosomes) are altered by chemical modifications. This research combines physics, chemistry, and molecular biology to understand fundamental mechanisms relevant to viral infection, gene regulation, and drug design.
Publication output has remained fairly steady over the past decade, fluctuating between about 7 and 14 papers per year with a modest increase in the most recent years (2024-2025).
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- BPS2026 – Kinetics mechanism of viral genome packaging by HIV-1 virions
Biophysical Journal · 2026
- BPS2026 – Histone-histone vs. histone-DNA interactions within the nucleosome probed at the single-molecule level
Biophysical Journal · 2026
- BPS2026 – LEDGF and HDGF2 differentially remodel histone-DNA interactions in H3K36 methylation-mimetic nucleosomes
Biophysical Journal · 2026
- BPS2026 – DNA condensation stabilizes the binding of HIV-1 nucleocapsid protein to promote phase separation and inhibit decondensation
Biophysical Journal · 2026
- BPS2026 - Force clamp experiments with optical tweezers confirm nanomolar affinity of doxorubicin to DNA
Biophysical Journal · 2026
- Aromatic ring transforms DNA binding modes of an octahedral rhodium complex
Biophysical Journal · 2026
- Single-molecule measurements of double-stranded DNA condensation
Biophysical Journal · 2025
- Binuclear ruthenium complex linker length tunes DNA threading intercalation kinetics
Biophysical Journal · 2025
- Diverse single-stranded nucleic acid binding proteins enable both stable protection and rapid exchange required for biological function
QRB Discovery · 2025
- BPS2025 - Optical tweezers measure multiple binding modes of diverse single-stranded nucleic acid binding proteins correlated with multiple biological protein functions
Biophysical Journal · 2025
- BPS2025 - LEDGF preferentially remodels histone-DNA interactions in methylated nucleosomes
Biophysical Journal · 2025
- BPS2025 - Hyperacylation from cellular metabolites destabilizes and unwinds nucleosomes
Biophysical Journal · 2025
- BPS2025 - LEDGF preferentially remodels histone-DNA interactions in methylated nucleosomes
Biophysical Journal · 2025
- BPS2025 - Optical tweezers measure multiple binding modes of diverse single-stranded nucleic acid binding proteins correlated with multiple biological protein functions
Biophysical Journal · 2025
- BPS2025 - Probing the interaction of doxorubicin with DNA using optical tweezers
Biophysical Journal · 2025
- Biophysical Journal×67
- Figshare×22
- Nucleic Acids Research×9
- Viruses×4
- Methods in molecular biology×4
- Jonathan Dickerhoff
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Clement Lin
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Buket Onel
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Danzhou Yang
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Besik Kankia
Biochemistry, Genetics and Molecular Biology · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
Claim or correct this profile