LabCompass

Jonathan Dickerhoff

Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette

OpenAlex ORCID
Mid career · publishing since 2014Rising activity
DNA and Nucleic Acid ChemistryAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene DeliveryRNA and protein synthesis mechanismsCancer therapeutics and mechanisms

Publications

62

Citations

1,110

Est. group size

~3

Recurring co-author estimate

Active years

13

Publishing since 2014

Research summary
AI-generated

Jonathan Dickerhoff studies unusual folded structures in DNA called G-quadruplexes, which form in the promoter regions of cancer-related genes such as MYC, PDGFR-β, and FGFR1, and can influence whether these genes are turned on or off. Using structural methods like NMR spectroscopy and mass spectrometry, his lab investigates how small molecules and proteins recognize and bind these DNA structures, with the goal of informing drug design strategies that target gene expression in cancer. This work sits at the intersection of structural biology, chemistry, and cancer biology.

G-quadruplex DNA structureCancer gene promoter regulationNMR structural biologySmall-molecule drug discoveryMass spectrometry of nucleic acids

Publication output has been fairly steady over the past decade, fluctuating between roughly 2 and 7 papers per year without a clear long-term increase or decline.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 4.6/year recently
2017: 6 publications172018: 4 publications182019: 7 publications7192020: 2 publications202021: 7 publications7212022: 3 publications222023: 7 publications7232024: 7 publications7242025: 3 publications252026: 3 publications26
Recent publications
Publishes in
  • Cancer Research×9
  • Chemistry - A European Journal×4
  • Nucleic Acids Research×3
  • Journal of the American Chemical Society×3
  • Open MIND×3
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This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 20, 2026.

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