Paul M.L. Janssen

This researcher studies how heart muscle contracts at the molecular level, focusing on proteins like myosin and myosin-binding protein-C that control the strength and timing of heartbeats. Much of the work examines what goes wrong in diseases such as hypertrophic cardiomyopathy, heart failure, and Barth syndrome (a rare mitochondrial disorder affecting the heart), often using human heart tissue samples, advanced imaging techniques, and molecular profiling. The research also touches on muscle-related disorders like muscular dystrophy and on engineered materials for heart valve repair.

Publication output declined markedly over the past decade, dropping from around 20-30 papers per year in 2017-2018 to about 5 per year from 2023-2025.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026