LabCompass

Michael G. Kearse

Biochemistry, Genetics and Molecular Biology · The Ohio State University

OpenAlex ORCID
Mid career · publishing since 2010Rising activity
RNA modifications and cancerRNA Research and SplicingRNA and protein synthesis mechanismsGenetics and Neurodevelopmental DisordersGenetic Neurodegenerative Diseases

Publications

38

Citations

1,498

Est. group size

~5

Recurring co-author estimate

Active years

17

Publishing since 2010

Research summary
AI-generated

Michael G. Kearse's research focuses on how cells make proteins from RNA, with particular attention to unconventional translation processes such as non-AUG start codon usage and RAN (repeat-associated non-AUG) translation linked to neurological diseases like fragile X syndrome and C9orf72-associated ALS/FTD. His lab also studies RNA-modifying enzymes and chemical marks on RNA (like m6A), ribosome behavior during stress, and proteins such as TOP3B and FMRP that regulate mRNA processing and translation. This work aims to understand molecular mechanisms underlying neurodevelopmental and neurodegenerative disorders and viral infection.

Non-canonical mRNA translation and ribosome mechanicsRNA modifications (epitranscriptomics) and RNA-binding proteinsRepeat-expansion disorders (fragile X, C9orf72)Topoisomerase 3β and mRNA-protein covalent intermediatesTranslation regulation in disease and viral infection (e.g., HIV-1)

Publication output has grown notably over the last decade, rising from about 1-2 papers per year in 2017-2021 to 5-7 per year in 2024-2026.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 4.4/year recently
2017: 2 publications172018: 2 publications182019: 2 publications192020: 1 publication202021: 1 publication212022: 4 publications222023: 3 publications232024: 5 publications242025: 7 publications7252026: 3 publications26
Recent publications
Publishes in
  • bioRxiv (Cold Spring Harbor Laboratory)×8
  • Journal of Biological Chemistry×4
  • Journal of Virology×3
  • Nucleic Acids Research×2
  • Wiley Interdisciplinary Reviews - RNA×2
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This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 19, 2026.

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