Jane E. Jackman
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
74
Citations
2,853
Est. group size
~3
Recurring co-author estimate
Active years
31
Publishing since 1996
Jane E. Jackman studies how transfer RNA (tRNA), a molecule that helps cells translate genetic code into proteins, is chemically modified and processed by specialized enzymes. Her lab investigates unusual enzymes such as 3'-5' RNA polymerases and tRNA methyltransferases (proteins that add small chemical tags to RNA), examining how they recognize and act on their RNA targets at a molecular level. This work combines biochemistry and structural biology to understand basic mechanisms of RNA processing relevant to cell function and evolution.
Publication output has fluctuated over the last decade but shows a recent increase, with several papers per year from 2023 through 2025.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- A comparison of <i>Dictyostelium discoideum</i> 3′-5′ RNA polymerases reveals a conserved tRNA <sup>His</sup> guanylyltransferase residue that plays a dual role in catalysis
RNA · 2026
- Metal Ion Requirement for Catalysis by 3′-5′ RNA Polymerases
Biochemistry · 2025
- Metal ion requirement for catalysis by 3′-5′ RNA polymerases
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- Structural mechanisms of DNA priming by polymerase α–primase
Structural Dynamics · 2025
- Decoding tRNA Modifications: Integrating Molecular, Biological, and Pathological Insights
Journal of Molecular Biology · 2025
- Mitochondrial tRNA processing: a neutral evolutionary ratchet innovation
Trends in Biochemical Sciences · 2025
- A comparison of <i>Dictyostelium discoideum</i> 3’-5’ RNA polymerases reveals a conserved tRNA <sup>His</sup> guanylyltransferase residue that plays a dual role in catalysis
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- Molecular basis of tRNA substrate recognition and modification by the atypical SPOUT methyltransferase Trm10
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- A mechanistic model of primer synthesis from catalytic structures of DNA polymerase α–primase
Nature Structural & Molecular Biology · 2024
- Thg1 family 3′–5′ RNA polymerases as tools for targeted RNA synthesis
RNA · 2024
- Thg1 family 3’-5’ RNA polymerases as tools for targeted RNA synthesis
bioRxiv (Cold Spring Harbor Laboratory) · 2024
- Abstract 1887 Substrate Recognition by Two 3' to 5' RNA Polymerases in Dictyostelium discoideum
Journal of Biological Chemistry · 2024
- Abstract 2091 Investigating molecular interactions with 3'-5' RNA polymerases in Dictyostelium Discoideum
Journal of Biological Chemistry · 2024
- tRNA m1G9 modification depends on substrate-specific RNA conformational changes induced by the methyltransferase Trm10
Journal of Biological Chemistry · 2023
- A tRNA-specific function for tRNA methyltransferase Trm10 is associated with a new tRNA quality control mechanism in <i>Saccharomyces cerevisiae</i>
RNA · 2023
- bioRxiv (Cold Spring Harbor Laboratory)×7
- RNA×5
- Journal of Biological Chemistry×5
- Biochemistry×2
- Nucleic Acids Research×2
- Aiswarya Krishnamohan
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Vollter Anastas
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Anita K. Hopper
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Michael G. Kearse
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Wen Zhang
Biochemistry, Genetics and Molecular Biology · Indiana University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
Claim or correct this profile