Vollter Anastas
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
24
Citations
109
Est. group size
~21
Recurring co-author estimate
Active years
11
Publishing since 2015
Vollter Anastas's research focuses on molecular mechanisms controlling gene expression in cancer cells, particularly how a protein modification process (phosphorylation) affects RNA splicing (a way cells edit genetic messages before making proteins) and how this influences tumor growth, immune signaling, and response to viral-based cancer therapies. The work also touches on microRNAs (small regulatory RNA molecules) and their role in blood cell disorders like leukemia. Notably, several of this researcher's key papers on lung cancer and RNA splicing have been formally retracted by the publishing journals.
Publication output was minimal before 2020, peaked with a burst of activity in 2020-2021, then declined and has remained at a low, steady level (1-3 papers per year) through 2025.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Retraction Note: AKT3-mediated IWS1 phosphorylation promotes the proliferation of EGFR-mutant lung adenocarcinomas through cell cycle-regulated U2AF2 RNA splicing
Nature Communications · 2022
- RETRACTED ARTICLE: AKT3-mediated IWS1 phosphorylation promotes the proliferation of EGFR-mutant lung adenocarcinomas through cell cycle-regulated U2AF2 RNA splicing
Nature Communications · 2021
- miR-181c regulates MCL1 and cell survival in GATA2 deficient cells
Journal of Leukocyte Biology · 2021
- RETRACTED ARTICLE: Phosphor-IWS1-dependent U2AF2 splicing regulates trafficking of CAR-E-positive intronless gene mRNAs and sensitivity to viral infection
Communications Biology · 2021
- Abstract PO088: Sensitivity of cancer cells to oncolytic viruses is defined by IWS1 phosphorylation dependent epigenetic regulation of U2AF2 splicing and nucleocytoplasmic export of type I IFN transcripts
Cancer Immunology Research · 2021
- Abstract PO010: The inhibition of IWS1 phosphorylation promotes genomic instability, the cGAS/STING pathway activation and PD-L1 levels, through the U2AF2 alternative RNA splicing and Sororin expression
Cancer Immunology Research · 2021
- Retraction Note: Phosphor-IWS1-dependent U2AF2 splicing regulates trafficking of CAR-E-positive intronless gene mRNAs and sensitivity to viral infection
Communications Biology · 2021
- Overexpression of the SETD2 WW domain inhibits the phosphor-IWS1/SETD2 interaction and the oncogenic AKT/IWS1 RNA splicing program
bioRxiv (Cold Spring Harbor Laboratory) · 2021
- KDM2B Silencing Elicits a Paracrine Mechanism Which Destabilizes SLUG, Promoting Differentiation of Basal-Like Breast Cancer Cells
bioRxiv (Cold Spring Harbor Laboratory) · 2020
- Abstract 3649: Alternative RNA splicing of U2AF2, induced by AKT3-phosphorylated IWS1, promotes tumor growth, by activating a CDCA5-pERK positive feedback loop
Cancer Research · 2020
- Abstract PO-011: IWS1 phosphorylation promotes tumor growth and predicts poor prognosis in EGFR mutant lung adenocarcinoma patients, through the epigenetic regulation of U2AF2 RNA splicing
Cancer Research · 2020
- IWS1 phosphorylation by AKT3 controls nuclear export of type I IFN mRNAs and sensitivity to oncolytic viral infection, by regulating the alternative RNA splicing of U2AF2
bioRxiv (Cold Spring Harbor Laboratory) · 2020
- Phospho-IWS1-dependent U2AF2 splicing is cell-cycle-regulated, promotes proliferation and predicts poor prognosis of EGFR- mutant lung adenocarcinoma
bioRxiv (Cold Spring Harbor Laboratory) · 2020
- Ibrutinib downregulates a subset of miRNA leading to upregulation of tumor suppressors and inhibition of cell proliferation in chronic lymphocytic leukemia
Leukemia · 2016
- Indolent Phenotype of RAS-Associated Autoimmune Leukoproliferative Disorder (RALD) Is Characterized By Single Somatic Mutations in RAS Genes with Absence of Cooperating Mutations
Blood · 2016
- bioRxiv (Cold Spring Harbor Laboratory)×7
- Cancer Research×5
- Nature Communications×2
- Communications Biology×2
- Cancer Immunology Research×2
- Yunlong Liu
Biochemistry, Genetics and Molecular Biology · Indiana University
- Evangelia Chavdoula
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Michael G. Kearse
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Anita K. Hopper
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Yue Wang
Biochemistry, Genetics and Molecular Biology · Indiana University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
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