LabCompass

Wolfgang Sadée

Biochemistry, Genetics and Molecular Biology · The Ohio State University

Established · publishing since 1967

Publications

497

Citations

23,382

Est. group size

~5

Recurring co-author estimate

Active years

59

Publishing since 1967

Research summary
AI-generated

This researcher studies how genetic variation affects drug transporters, receptors, and metabolizing enzymes, with a particular focus on G-protein-coupled receptors (cell-surface proteins that relay signals from hormones and drugs into cells) and their 'ligand-free' signaling activity even without a bound drug or hormone. Related work examines gene regulation by microRNAs in cancer drug resistance, and genetic markers linked to diseases such as coronary artery disease and tuberculosis. The work combines pharmacology, genetics, and genomics to understand individual differences in drug response.

Pharmacogenetics and drug metabolismG-protein-coupled receptor signalingMembrane transporters and drug resistanceMicroRNA regulation in cancerFunctional genomics of disease-associated variants

Publication output has fluctuated over the past decade, dipping around 2021 before a notable spike in 2023, then dropping sharply in 2024-2025, suggesting slowing recent activity.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 5.4/year recently
2017: 12 publications172018: 11 publications182019: 8 publications192020: 10 publications202021: 3 publications212022: 8 publications222023: 16 publications16232024: 1 publication242025: 2 publications2526
Publishes in
  • PLoS ONE×4
  • Molecules×3
  • Pharmaceutical Research×3
  • BMC Genomics×3
  • bioRxiv (Cold Spring Harbor Laboratory)×3
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This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 19, 2026.

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