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Arryn T. Blaine

Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette

OpenAlex ORCID
Early career · publishing since 2018
Receptor Mechanisms and SignalingNeuropeptides and Animal PhysiologyPharmacological Receptor Mechanisms and EffectsProtein Kinase Regulation and GTPase SignalingNeurotransmitter Receptor Influence on Behavior

Publications

16

Citations

129

Est. group size

~1

Recurring co-author estimate

Active years

7

Publishing since 2018

Research summary
AI-generated

Arryn T. Blaine's research focuses on opioid receptors, particularly the delta and mu subtypes, examining how different drug-like molecules bind to and activate these receptors in the brain. A recurring theme is understanding how certain opioid drugs can cause seizures, and how signaling proteins called beta-arrestins contribute to both therapeutic effects and side effects. This work combines chemistry (designing new receptor-targeting molecules) with pharmacology (testing how they affect brain signaling and behavior in animal models).

Opioid receptor pharmacology (delta and mu receptors)Beta-arrestin signaling and receptor biasDrug-induced seizures and neurotoxicityMedicinal chemistry of receptor-selective ligandsBehavioral and neurochemical effects of psychoactive substances

Publication output rose to a peak around 2019-2021 but has slowed in recent years, averaging fewer than one publication per year over the last five years.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 0.6/year recently
172018: 3 publications182019: 4 publications4192020: 2 publications202021: 4 publications4212022: 1 publication222023: 1 publication232024: 1 publication242526
Recent publications
Publishes in
  • The FASEB Journal×4
  • Frontiers in Pharmacology×2
  • ChemRxiv×2
  • Journal of Biological Chemistry×1
  • Neuropharmacology×1
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By research-topic overlap
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This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 20, 2026.

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