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Vikki M. Weake

Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette

OpenAlex ORCID
Mid career · publishing since 2005
Genomics and Chromatin DynamicsNeurobiology and Insect Physiology ResearchGenetics, Aging, and Longevity in Model OrganismsCircadian rhythm and melatoninRNA Research and Splicing

Publications

114

Citations

2,344

Est. group size

~9

Recurring co-author estimate

Active years

22

Publishing since 2005

Research summary
AI-generated

Vikki M. Weake studies how chromatin (the packaging of DNA with proteins that controls gene activity) and epigenetic modifications like histone methylation and acetylation influence gene expression rhythms, aging, and retinal degeneration, mainly using the fruit fly Drosophila melanogaster as a model organism. Her work focuses particularly on how the eye's daily (circadian) gene expression patterns change with age and light exposure, and on enzymes such as Gcn5 and AHCY that regulate these chromatin changes. This research aims to understand fundamental mechanisms linking gene regulation to tissue aging and sensory decline.

Chromatin and histone modificationDrosophila as a model organismCircadian rhythms and gene expressionAging and retinal degenerationEpigenetics and metabolism

Publication output has fluctuated over the past decade, dropping from a peak in 2017 to lower and irregular annual counts since, with a gap in 2024 followed by renewed output in 2025-2026.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 4.6/year recently
2017: 31 publications31172018: 12 publications182019: 3 publications192020: 8 publications202021: 10 publications212022: 6 publications222023: 5 publications23242025: 9 publications252026: 3 publications26
Recent publications
Publishes in
  • Figshare×15
  • bioRxiv (Cold Spring Harbor Laboratory)×9
  • Purdue University Research Repository×7
  • Journal of Biological Chemistry×6
  • The FASEB Journal×5
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This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 20, 2026.

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