Ann L. Kirchmaier
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
Publications
30
Citations
1,792
Est. group size
—
Recurring co-author estimate
Active years
30
Publishing since 1995
Ann L. Kirchmaier studies how DNA is packaged with proteins into chromatin and how this packaging influences gene silencing (turning genes off) and the cell's response to DNA damage, largely using the yeast Saccharomyces cerevisiae as a model organism. Her work examines specific molecular modifications to histone proteins, such as acetylation and methylation, and how enzymes and assembly factors that add or interpret these marks affect genome stability and gene regulation. This research is relevant to understanding fundamental cellular processes that, when disrupted, can contribute to diseases involving genome instability.
Publication output has been low and irregular over the last decade, with several years showing no recorded output and a recent average of less than one publication per year.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- CAF-1 and Rtt101p function within the replication-coupled chromatin assembly network to promote H4 K16ac, preventing ectopic silencing
PLoS Genetics · 2020
- Tolerance of DNA Replication Stress Is Promoted by Fumarate Through Modulation of Histone Demethylation and Enhancement of Replicative Intermediate Processing in<i>Saccharomyces cerevisiae</i>
Genetics · 2019
- Modulation of Gene Silencing by Cdc7p via H4 K16 Acetylation and Phosphorylation of Chromatin Assembly Factor CAF-1 in <i>Saccharomyces cerevisiae</i>
Genetics · 2019
- Effects of H4K16 and Gene Mutation on Sensitivity to DNA Damaging Agents and Silencing
The FASEB Journal · 2017
- Synthesis and Application of Cell-Permeable Metabolites for Modulating Chromatin Modifications Regulated by α-Ketoglutarate-Dependent Enzymes
Methods in pharmacology and toxicology · 2016
- Genetics×2
- PLoS ONE×1
- PLoS Genetics×1
- Methods in pharmacology and toxicology×1
- The FASEB Journal×1
- Paula A. Agudelo Garcia
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Brian R. Calvi
Biochemistry, Genetics and Molecular Biology · Indiana University
- Liudmila V. Popova
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Sungyun Kang
Biochemistry, Genetics and Molecular Biology · Indiana University
- Christine E. Cucinotta
Biochemistry, Genetics and Molecular Biology · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 20, 2026.
Claim or correct this profile