LabCompass

Brian R. Calvi

Biochemistry, Genetics and Molecular Biology · Indiana University

OpenAlex ORCID
Established · publishing since 1991
Genomics and Chromatin DynamicsEpigenetics and DNA MethylationMicrotubule and mitosis dynamicsDNA Repair MechanismsCancer-related Molecular Pathways

Publications

67

Citations

8,637

Est. group size

—

Recurring co-author estimate

Active years

35

Publishing since 1991

Research summary
AI-generated

Brian R. Calvi studies how cells control their division and copy their DNA, using the fruit fly Drosophila as a model organism. His work focuses on 'endocycles' (a process where cells copy their DNA repeatedly without dividing, producing extra copies of the genome, called polyploidy) and how disruptions to normal cell-cycle control relate to genome instability, tissue growth, and cancer. He also examines related pathways such as the p53 stress-response gene, apoptosis (programmed cell death), and senescence (cell aging arrest).

Cell cycle and endoreplication controlPolyploidy and genome instabilityCancer-related molecular pathwaysp53, apoptosis and stress responsesDrosophila developmental genetics

Publication activity has remained fairly steady over the last decade, averaging around three to five papers per year with no strong upward or downward trend.

Generated by claude-opus-4-8 from public bibliographic data · Jul 9, 2026

Funding
Public award records

Current awards run through May 2029 — about 3 years of funding on record from today. Awards are often renewed, so this is what is currently public, not a forecast.

  • ActiveNIH R35GM152255through May 2029 · $396k awarded

    Cell cycle and checkpoint variations in development and disease

3 earlier awards
  • NIH R01GM113107Aug 2015 – May 2024 · $318k awarded

    Polypoid cell cycle regulation and genome instability

  • NIH R01GM124220Sep 2017 – Jul 2022 · $319k awarded

    Post-transcriptional Control of Adaptive Tissue Growth

  • NIH R01GM061290Jul 2000 – Aug 2012 · $284k awarded

    Chromatin regulated DNA replication

Matched to public NIH RePORTER and NSF records by name and institution. Awards from other agencies are not shown, and a match is not always found — this list may be incomplete.

In context
Among 1,724 established Biochemistry, Genetics and Molecular Biology PIs within our index
Citations: 8,637cohort median 3,385
h-index: 32cohort median 27
Publications / year (recent): 3.2cohort median 4.6

Typically publishes in teams of ~3 · 52% small-team papers (≤3 authors) · across 11 venues

Publication cadence
Publications per year over the last 10 years — averaging 3.2/year recently
2017: 2 publications172018: 5 publications5182019: 5 publications5192020: 3 publications202021: 1 publication212022: 5 publications5222023: 3 publications232024: 5 publications5242025: 3 publications2526
Collaborators per year
Distinct co-authors at Indiana University each year — a rough indication of whether the group around this researcher has been growing or contracting. An estimate from co-authorship, not a roster: collaborators are not necessarily lab members, and recent years can be under-counted while indexing catches up.
2017: 0 collaborators at the same institution2018: 0 collaborators at the same institution2019: 0 collaborators at the same institution2020: 2 collaborators at the same institution2021: 3 collaborators at the same institution2022: 0 collaborators at the same institution2023: 1 collaborator at the same institution2024: 0 collaborators at the same institution2025: 1 collaborator at the same institution1719212325
Recent publications
Publishes in
  • Genetics×8
  • bioRxiv (Cold Spring Harbor Laboratory)×7
  • Nucleic Acids Research×3
  • G3 Genes Genomes Genetics×3
  • PLoS Genetics×2
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This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Sep 1, 2026.

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