Publications
151
Citations
1,247
Est. group size
—
Recurring co-author estimate
Active years
16
Publishing since 2011
Valerie P. O'Brien studies how the stomach lining changes in response to infection by the bacterium Helicobacter pylori, focusing on how normal stomach cells transform into abnormal ('metaplastic') cell states that can precede gastric cancer. Her work uses single-cell profiling and animal models to identify specific cell types involved in stomach tissue regeneration, inflammation, and bacterial colonization. This research is relevant to students interested in gastroenterology, infectious disease, cancer biology, and cell biology techniques like single-cell sequencing.
Publication counts were low and steady (2-5 per year) from 2017-2022, then spiked dramatically in 2023 (likely due to a single study generating many linked supplementary data records) before returning to a low, steady rate in 2024-2026.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Bad bugs mean business: gastric cancer is an intended consequence of <i>Helicobacter pylori</i> infection
Infection and Immunity · 2026
- <i>Muc6</i> -expressing gastric isthmus progenitors contribute to regeneration and metaplasia supported by myeloid-mesenchymal interactions
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- Metaplasia Enables Stomach Colonization by <i>Fusobacterium animalis</i>
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- EP28 GIF+GSII+ CELLS IN THE ACUTE GASTRIC METAPLASIA DO NOT SERVE AS AN ORIGIN OF MUCOSAL REGENERATION AND KRAS- OR H. PYLORI-INDUCED METAPLASIA.
Gastroenterology · 2024
- Single-cell Profiling Uncovers a <i>Muc4</i> -Expressing Metaplastic Gastric Cell Type Sustained by <i>Helicobacter pylori</i> -driven Inflammation
Cancer Research Communications · 2023
- Characterization of <scp>HOXB13</scp> expression patterns in localized and metastatic castration‐resistant prostate cancer
The Journal of Pathology · 2023
- Helicobacter pylori Chronic Infection Selects for Effective Colonizers of Metaplastic Glands
mBio · 2023
- Figure S10 from Single-cell profiling uncovers a Muc4-expressing metaplastic gastric cell type sustained by Helicobacter pylori-driven inflammation
2023
- Table S2 from Single-cell profiling uncovers a Muc4-expressing metaplastic gastric cell type sustained by Helicobacter pylori-driven inflammation
2023
- Table S8 from Single-cell profiling uncovers a Muc4-expressing metaplastic gastric cell type sustained by Helicobacter pylori-driven inflammation
2023
- Table S1 from Single-cell profiling uncovers a Muc4-expressing metaplastic gastric cell type sustained by Helicobacter pylori-driven inflammation
2023
- Figure S9 from Single-cell profiling uncovers a Muc4-expressing metaplastic gastric cell type sustained by Helicobacter pylori-driven inflammation
2023
- Figure S2 from Single-cell profiling uncovers a Muc4-expressing metaplastic gastric cell type sustained by Helicobacter pylori-driven inflammation
2023
- Table S3 from Single-cell profiling uncovers a Muc4-expressing metaplastic gastric cell type sustained by Helicobacter pylori-driven inflammation
2023
- Figure S4 from Single-cell profiling uncovers a Muc4-expressing metaplastic gastric cell type sustained by Helicobacter pylori-driven inflammation
2023
- bioRxiv (Cold Spring Harbor Laboratory)×7
- PLoS Pathogens×2
- Nature Microbiology×2
- Infection and Immunity×2
- Frontiers in Cellular and Infection Microbiology×2
- Shivendra Tenguria
Medicine · Purdue University West Lafayette
- Samuel A. Miller
Medicine · Indiana University
- Rajkumar Dhanaraju
Medicine · Indiana University
- Eleazar E. Montalvan-Sanchez
Medicine · Indiana University
- Christopher A. Ladaika
Medicine · Indiana University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 20, 2026.
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