LabCompass

Sarah J. Shepherd

Biochemistry, Genetics and Molecular Biology · The Ohio State University

OpenAlex ORCID
Mid career · publishing since 2006Rising activity
RNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesLipid Membrane Structure and BehaviorNanoparticle-Based Drug DeliveryVestibular and auditory disorders

Publications

50

Citations

2,513

Est. group size

—

Recurring co-author estimate

Active years

21

Publishing since 2006

Research summary
AI-generated

Sarah J. Shepherd's research focuses on lipid nanoparticles (LNPs), which are tiny fat-based particles used to deliver genetic material like mRNA or siRNA into cells for therapeutic purposes, such as vaccines and gene therapies. Her work spans the design, manufacturing, and biophysical characterization of these nanoparticles, including microfluidic (small-scale fluid-handling chip) production methods and studies of how nanoparticle structure relates to their function in delivering drugs to specific tissues like the lungs, liver, and bone marrow.

Lipid nanoparticle design and characterizationmRNA and RNA-based drug deliveryMicrofluidic manufacturing of nanoparticlesNanoparticle biophysics and structure-function analysisNanomedicine for vaccines and targeted therapy

Publication output has grown substantially over the past decade, rising from about 1-2 papers per year before 2021 to a peak of 9 in 2023, with continued strong activity through 2024-2025.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 5.6/year recently
2017: 1 publication172018: 1 publication182019: 2 publications192020: 2 publications202021: 4 publications212022: 4 publications222023: 9 publications9232024: 8 publications242025: 5 publications252026: 2 publications26
Recent publications
Publishes in
  • Nature Communications×4
  • bioRxiv (Cold Spring Harbor Laboratory)×4
  • Patient Education and Counseling×3
  • Proceedings of the National Academy of Sciences×2
  • Journal of Biomedical Materials Research Part A×2
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This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 19, 2026.

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