Robert J. Lee
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
338
Citations
17,779
Est. group size
~2
Recurring co-author estimate
Active years
61
Publishing since 1965
Robert J. Lee's work focuses on developing nanoparticle and lipid-based delivery systems for drugs and nucleic acids (like antisense oligonucleotides and small RNAs) to treat conditions such as cancer, osteoarthritis, and neurodegenerative diseases. Much of the research is applied pharmaceutical science, combining formulation techniques (such as solid lipid nanoparticles and solid dispersions) with testing in cell and animal models to improve how therapeutics are delivered and absorbed in the body. The publication record includes both full research articles and conference abstracts, often in collaboration with industry or clinical research groups.
Publication output has declined over the past decade, dropping from around 25 papers per year in 2017-2019 to roughly 8 per year on average over the last five years, with a notable dip in 2024 before a slight rebound in 2025.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Harnessing the Potential of Exosomes in Therapeutic Interventions for Brain Disorders
International Journal of Molecular Sciences · 2025
- Virus-inspired lipopeptide-derived nucleic acid delivery to cartilage for osteoarthritis therapy
Nature Communications · 2025
- Decellularized dermis allograft for the treatment of venous leg ulceration: the DAVE RCT
British journal of surgery · 2025
- Jet-milling co-grounds of APIs with polysorbate 80, lecithin and sucrose esters: Particle characteristics and impacts on agglomeration and dissolution efficiency
Advanced Powder Technology · 2025
- Small nucleic acid therapeutics: delivery breakthroughs, clinical translation, and future paradigms in precision medicine
International Journal of Pharmaceutics · 2025
- Novel potent and selective inhibitors targeting FLT3 for AML therapy.
Journal of Clinical Oncology · 2025
- Cellular-nanoporation boosts high-yield RVG-modified exosomes for multifunctional α-synuclein scavengers against Parkinson's disease
Chinese Chemical Letters · 2025
- Surface Solid Dispersion of Ketoconazole on Trehalose Dihydrate using Spray Drying to Achieve Enhanced Dissolution Rate
AAPS PharmSciTech · 2024
- Enhanced dissolution rates of glibenclamide through solid dispersions on microcrystalline cellulose and mannitol, combined with phosphatidylcholine
Drug Development and Industrial Pharmacy · 2024
- Abstract 3252: Anti-tumor effect of the combination of a lipid nanoparticle suspension of an AKT-1 antisense oligonucleotide (WGI-0301) with tyrosine kinase inhibitors in an orthotopic murine tumor model
Cancer Research · 2024
- Dual-Ligand-Functionalized Liposomes Based on Glycyrrhetinic Acid and cRGD for Hepatocellular Carcinoma Targeting and Therapy
Molecular Pharmaceutics · 2023
- Abstract 5123: The anti-tumor and anti-angiogenic effects of a lipid nanoparticle suspension of an AKT-1 anti-sense oligonucleotide
Cancer Research · 2023
- Abstract 701: Evaluation of an AKT-1 antisense oligonucleotide in combination with Lenvatinib and Everolimus in Renca-luciferase syngeneic orthotopic murine tumor model
Cancer Research · 2023
- Abstract A174: Antitumor activity of lipid nanoparticle-delivered anti-miR-21
Molecular Cancer Therapeutics · 2023
- Supplementary Figure 1B from Depletion of Peripheral Macrophages and Brain Microglia Increases Brain Tumor Titers of Oncolytic Viruses
2023
- Nanomedicine Nanotechnology Biology and Medicine×8
- International Journal of Pharmaceutics×8
- International Journal of Nanomedicine×7
- Molecules×6
- Anticancer Research×6
- Krishan Kumar
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Shi Du
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Sarah J. Shepherd
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Congcong Xu
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Fengmei Pi
Biochemistry, Genetics and Molecular Biology · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
Claim or correct this profile