S. Dhar
Agricultural and Biological Sciences · The Ohio State University
Publications
31
Citations
271
Est. group size
~5
Recurring co-author estimate
Active years
55
Publishing since 1970
S. Dhar's recent work uses large-scale variant-effect experiments to study how mutations affect protein function relevant to human disease, including BRCA1 (a gene linked to breast and ovarian cancer risk) and TAP2 (a protein involved in presenting pieces of pathogens or tumor cells to the immune system). This research applies 'multiplexed assays of variant effect,' a technique that tests thousands of genetic variants simultaneously to determine which ones disrupt normal protein activity, such as DNA repair or immune antigen presentation.
Publication activity appears to have begun only in 2023 and 2024, with no recorded output in the preceding years of the last decade, suggesting a recent and still-emerging publication record rather than a long-established steady pattern.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Multiplexed functional analysis of TAP2 variants in regulating MHC-I cell surface abundance reveals overexpression of PLK1 downregulates antigen presentation
bioRxiv (Cold Spring Harbor Laboratory) · 2024
- Identification of TAP2 protein variants resistant to inhibition by the HSV1 ICP47 protein
bioRxiv (Cold Spring Harbor Laboratory) · 2024
- DNA repair function scores for 2172 variants in the BRCA1 amino-terminus
PLoS Genetics · 2023
- Multiplexed assay of variant effect reveals residues of functional importance in the BRCA1 coiled-coil and serine cluster domains
PLoS ONE · 2023
- DNA Repair Function Scores for 2172 Variants in the BRCA1 Amino-Terminus
bioRxiv (Cold Spring Harbor Laboratory) · 2023
- bioRxiv (Cold Spring Harbor Laboratory)×3
- PLoS Genetics×1
- PLoS ONE×1
- Maria V. Murgia
Agricultural and Biological Sciences · Purdue University West Lafayette
- Yasuko Rikihisa
Immunology and Microbiology · The Ohio State University
- Risa Pesapane
Immunology and Microbiology · The Ohio State University
- Oghenekaro Omodior
Immunology and Microbiology · Indiana University
- Alexander Welker Biondo
Immunology and Microbiology · Purdue University West Lafayette
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
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