LabCompass

Ross C. Larue

Immunology and Microbiology · The Ohio State University

OpenAlex ORCID
Mid career · publishing since 2001
HIV Research and TreatmentHIV/AIDS drug development and treatmentBiochemical and Molecular ResearchCRISPR and Genetic EngineeringVirus-based gene therapy research

Publications

49

Citations

2,107

Est. group size

~2

Recurring co-author estimate

Active years

26

Publishing since 2001

Research summary
AI-generated

Ross C. Larue studies how retroviruses like HIV integrate their genetic material into host cells, using this knowledge to develop antiviral drugs and gene therapy tools. His work includes designing inhibitors that block viral integration machinery and engineering modified retroviral integrases to insert therapeutic genes at specific genome locations, such as for treating cystic fibrosis. He also investigates related topics like drug toxicity mechanisms and host cell factors that support or resist viral infection.

Retroviral integration and gene therapy vectorsHIV-1 structural biology and drug resistanceAntiviral drug discovery (integrase and BET bromodomain inhibitors)Host-virus interaction factorsSite-specific gene delivery for genetic disease

Publication output has fluctuated over the past decade, peaking around 2021 with a subsequent slowdown, though a small resurgence appears in the most recent years (2024-2026).

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 2.2/year recently
2017: 2 publications17182019: 4 publications192020: 1 publication202021: 7 publications7212022: 4 publications222023: 1 publication232024: 2 publications242025: 1 publication252026: 3 publications26
Recent publications
Publishes in
  • bioRxiv (Cold Spring Harbor Laboratory)×3
  • Journal of Biological Chemistry×2
  • Journal of Cystic Fibrosis×2
  • Cell×1
  • Bioconjugate Chemistry×1
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By research-topic overlap

This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 19, 2026.

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