Pei-Ru Jin
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
Publications
14
Citations
598
Est. group size
~4
Recurring co-author estimate
Active years
10
Publishing since 2017
Pei-Ru Jin's research focuses on how gut bacteria and their metabolic byproducts influence human disease, especially colorectal cancer and liver toxicity. Recent work examines how a bacterium called Fusobacterium nucleatum produces molecules that activate a receptor (AHR) linked to colon cancer cell growth, and how other gut microbial metabolites affect liver drug-processing enzymes and drug-induced liver damage. Earlier work involved designing nanoparticle-based drug delivery systems for treating liver fibrosis and cancer.
Publication output was low and intermittent from 2017-2023 but has increased noticeably in 2024-2026, suggesting growing recent research activity.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- ROLE OF THE GUT MICROBIOTA-ARYL HYDROCARBON RECEPTOR AXIS IN COLORECTAL CANCER PROGRESSION
Open MIND · 2026
- ROLE OF THE GUT MICROBIOTA-ARYL HYDROCARBON RECEPTOR AXIS IN COLORECTAL CANCER PROGRESSION
Purdue · 2026
- Development of a High-Throughput Size-Exclusion Chromatography–Mass Spectrometry Workflow for Real-Time Monitoring of Bioconjugation of Cysteine-Based Antibody–Drug Conjugates
Bioconjugate Chemistry · 2026
- <i>Fusobacterium nucleatum</i> produces previously unappreciated AHR-activating metabolites and promotes CRC cell proliferation via the AHR-TERT axis
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- Aryl Hydrocarbon Receptor Signaling Activated by Fusobacterium Nucleatum Metabolite Aggravates Colorectal Cancer Cell Proliferation and Tumor Growth (Abstract ID: 159194)
Journal of Pharmacology and Experimental Therapeutics · 2025
- Gut bacterial metabolite 3-Phenylpropionic acid inhibits cytochrome P450 2E1 expression and attenuates acetaminophen-induced cytotoxicity in primary mouse hepatocytes
Drug Metabolism and Pharmacokinetics · 2025
- Gut microbial metabolites activate pregnane X receptor to increase CYP3A4 expression in the liver
Drug Metabolism and Pharmacokinetics · 2025
- The Discovery of Gut Microbial Metabolites as Modulators of Host Susceptibility to Acetaminophen-Induced Hepatotoxicity
Drug Metabolism and Disposition · 2024
- Fusobacterium nucleatum Metabolites Activate Aryl Hydrocarbon Receptor and Promote Colorectal Cancer Cell Proliferation
Journal of Pharmacology and Experimental Therapeutics · 2024
- Delivery of sorafenib by myofibroblast-targeted nanoparticles for the treatment of renal fibrosis
Journal of Controlled Release · 2022
- Cinchona Alkaloid-Inspired Urea-Containing Autophagy Inhibitor Shows Single-Agent Anticancer Efficacy
Journal of Medicinal Chemistry · 2021
- Combined delivery of sorafenib and a MEK inhibitor using CXCR4-targeted nanoparticles reduces hepatic fibrosis and prevents tumor development
UNC Libraries · 2020
- Delivery of nitric oxide with a nanocarrier promotes tumour vessel normalization and potentiates anti-cancer therapies
Nature Nanotechnology · 2019
- Combined delivery of sorafenib and a MEK inhibitor using CXCR4-targeted nanoparticles reduces hepatic fibrosis and prevents tumor development
Theranostics · 2017
- Journal of Pharmacology and Experimental Therapeutics×2
- Drug Metabolism and Pharmacokinetics×2
- Nature Nanotechnology×1
- Theranostics×1
- Journal of Controlled Release×1
- Carmen L. Wickware
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Andrew Gold
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Amy R. Mackos
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Amna Bibi
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Andrea R. Merchak
Biochemistry, Genetics and Molecular Biology · Indiana University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 20, 2026.
Claim or correct this profile