Nipun Malhotra
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
25
Citations
275
Est. group size
~8
Recurring co-author estimate
Active years
9
Publishing since 2018
Nipun Malhotra's work spans two main areas: structural biology of parasite enzymes (aminoacyl-tRNA synthetases) as antimalarial and anti-parasitic drug targets, and cardiac molecular biology, particularly ion channels and calcium-handling proteins involved in heart rhythm disorders. The research combines protein crystallography and biochemical structure-function studies with translational applications in infectious disease and cardiovascular disease.
Publication output has been variable but generally active over the past decade, with a notable cluster in 2018 and 2023, and a steady output of a few papers per year in the more recent period.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- PO-04-227 IMPACT OF G-PROTEIN-GATED INWARDLY RECTIFYING POTASSIUM (GIRK) SUBUNIT COMPOSITION ON ACETYLCHOLINE-ACTIVATED POTASSIUM CHANNEL (KACH) FUNCTION
Heart Rhythm · 2026
- Evaluation of Tideglusib as a Disease Modifying Therapy in Murine Models of Arrhythmogenic Cardiomyopathy
JACC Basic to Translational Science · 2025
- Abstract Fri096: CLIC2 AS A NOVEL REGULATOR OF RYR2 AND SR Ca <sup>2+</sup> HOMEOSTASIS IN CARDIAC PHYSIOLOGY
Circulation Research · 2025
- ATP mimetics targeting prolyl-tRNA synthetases as a new avenue for antimalarial drug development
iScience · 2024
- Atrial fibrillation in Black American patients: A review of genetics, risk factors, and outcomes
Heart Rhythm · 2024
- Relevance of KCNJ5 in Pathologies of Heart Disease
International Journal of Molecular Sciences · 2023
- Biochemical Structure and Function of TRAPP Complexes in the Cardiac System
JACC Basic to Translational Science · 2023
- Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis
PLoS Pathogens · 2023
- Double drugging of prolyl-tRNA synthetase provides a new paradigm for anti-infective drug development
PLoS Pathogens · 2022
- Protein Phosphatase Signaling in Cardiac Myocytes
2022
- Structural basis of malaria parasite phenylalanine tRNA-synthetase inhibition by bicyclic azetidines
Nature Communications · 2021
- Conformational heterogeneity in apo and drug-bound structures of <i>Toxoplasma gondii</i> prolyl-tRNA synthetase
Acta Crystallographica Section F Structural Biology Communications · 2019
- Drug targeting of one or more aminoacyl-tRNA synthetase in the malaria parasite Plasmodium falciparum
Drug Discovery Today · 2018
- Specific Stereoisomeric Conformations Determine the Drug Potency of Cladosporin Scaffold against Malarial Parasite
Journal of Medicinal Chemistry · 2018
- CCDC 1588652: Experimental Crystal Structure Determination
The Cambridge Structural Database · 2018
- The Cambridge Structural Database×4
- Heart Rhythm×3
- PLoS Pathogens×2
- JACC Basic to Translational Science×2
- bioRxiv (Cold Spring Harbor Laboratory)×2
- Ila Marathe
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Abhishek Majumdar
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Bei Liu
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Barbara L. Golden
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Juan Xie
Biochemistry, Genetics and Molecular Biology · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
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