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Barbara L. Golden

Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette

OpenAlex ORCID
Established · publishing since 1974
RNA and protein synthesis mechanismsRNA modifications and cancerBacteriophages and microbial interactionsRNA Research and SplicingDNA and Nucleic Acid Chemistry

Publications

63

Citations

4,199

Est. group size

—

Recurring co-author estimate

Active years

51

Publishing since 1974

Research summary
AI-generated

Barbara L. Golden studies ribozymes, which are RNA molecules that can catalyze chemical reactions like proteins do, focusing on how their three-dimensional structures enable functions such as cutting RNA or even mimicking enzymes involved in protein synthesis. Her work combines structural biology, biochemistry, and computational modeling to understand catalytic RNA molecules like the hammerhead ribozyme and group I introns. This research contributes to broader understanding of RNA's role in molecular biology and potential applications in RNA engineering.

Catalytic RNA (ribozymes)RNA structure and functionRNA-protein and RNA-metal ion interactionsMolecular simulation of nucleic acidsRNA engineering

Publication output has been low and irregular over the last decade, with sparse yearly output (averaging about 0.2 papers per year in the last five years) and gaps in several years.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 0.2/year recently
2017: 1 publication17182019: 2 publications2192020: 1 publication202021: 1 publication2122232024: 1 publication242526
Recent publications
Publishes in
  • Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature×2
  • RNA×1
  • Biochemistry×1
  • Elsevier eBooks×1
  • bioRxiv (Cold Spring Harbor Laboratory)×1
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By research-topic overlap
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This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 20, 2026.

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