Michael G. Poirier
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
188
Citations
5,494
Est. group size
~17
Recurring co-author estimate
Active years
52
Publishing since 1975
Michael G. Poirier's research focuses on how DNA is packaged into chromatin and how proteins like transcription factors and pioneer factors gain access to genetic information wrapped around histone proteins (nucleosomes). His lab also develops DNA nanotechnology, such as DNA origami, using single-molecule imaging and biophysical techniques to study these dynamic molecular interactions. This work bridges biochemistry, biophysics, and molecular biology to understand fundamental mechanisms of gene regulation and to engineer nanoscale DNA-based devices.
Publication output has grown over the past decade, rising from about 5 papers per year in 2017 to a peak of 19 in 2023, with continued high activity averaging over 11 papers per year in the last five years.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Design and single-molecule characterization of dynamic DNA origami assemblies for signal transmission
Biophysical Journal · 2024
- Mechanism of DNA origami folding elucidated by mesoscopic simulations
Nature Communications · 2024
- Aberrant expression of histone H2B variants reshape chromatin and alter oncogenic gene expression programs
bioRxiv (Cold Spring Harbor Laboratory) · 2024
- Basic helix-loop-helix pioneer factors interact with the histone octamer to invade nucleosomes and generate nucleosome depleted regions.
Zenodo (CERN European Organization for Nuclear Research) · 2023
- Basic helix-loop-helix pioneer factors interact with the histone octamer to invade nucleosomes and generate nucleosome depleted regions.
Zenodo (CERN European Organization for Nuclear Research) · 2023
- Mechanism of DNA origami folding elucidated by mesoscopic simulations
bioRxiv (Cold Spring Harbor Laboratory) · 2023
- Single molecule evidence for linker histone H1 DNA sliding and nucleosomal bypassing regulated by the C-terminal disordered domain
Biophysical Journal · 2023
- Delivery and imaging of functionalized DNA origami in cells
Biophysical Journal · 2023
- Basic helix-loop-helix pioneer factors interact with the histone octamer to invade nucleosomes and generate nucleosome-depleted regions
Molecular Cell · 2023
- The nucleosome unwrapping free energy landscape defines distinct regions of transcription factor accessibility and kinetics
Nucleic Acids Research · 2023
- Steric Communication between Dynamic Components on DNA Nanodevices
ACS Nano · 2023
- Development of convergent hybrid phase ligation for efficient and convenient total synthesis of proteins
Peptide Science · 2023
- H1.0 C Terminal Domain Is Integral for Altering Transcription Factor Binding within Nucleosomes
Biochemistry · 2022
- Basic helix-loop-helix pioneer factors interact with the histone octamer to invade nucleosomes and generate nucleosome depleted regions
bioRxiv (Cold Spring Harbor Laboratory) · 2022
- Steric Communication between Dynamic Components on DNA nanodevices
bioRxiv (Cold Spring Harbor Laboratory) · 2022
- bioRxiv (Cold Spring Harbor Laboratory)×21
- Biophysical Journal×17
- Nucleic Acids Research×8
- Nature Communications×7
- Zenodo (CERN European Organization for Nuclear Research)×6
- Justin A. North
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Ruo-Wen Chen
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Chongli Yuan
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Gabriel E. Zentner
Biochemistry, Genetics and Molecular Biology · Indiana University
- Minou Bina
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
Claim or correct this profile