LabCompass

Chongli Yuan

Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette

OpenAlex ORCID
Established · publishing since 1997Rising activity
Genomics and Chromatin DynamicsEpigenetics and DNA MethylationDNA and Nucleic Acid ChemistryNeuroscience and Neuropharmacology ResearchHeavy Metal Exposure and Toxicity

Publications

147

Citations

4,976

Est. group size

~55

Recurring co-author estimate

Active years

30

Publishing since 1997

Research summary
AI-generated

Chongli Yuan's research focuses on the molecular and cellular biology of epigenetics — the chemical modifications to DNA and the proteins that package it (chromatin) that control which genes are turned on or off. The lab develops tools such as fluorescent biosensors and probes to watch these epigenetic changes happen in real time inside living cells, and applies these tools to problems like Alzheimer's disease, spinal cord injury, chronic pain, cancer drug resistance, and heavy metal toxicity. Much of the work combines protein engineering, imaging, and genomics to link epigenetic changes to disease processes and to build lab models (like brain organoids) for studying and testing treatments.

Epigenetics and DNA/histone methylationChromatin structure and dynamicsBiosensor and probe engineering for live-cell imagingNeurological disease modeling (Alzheimer's, spinal cord injury, pain)Environmental toxicology (heavy metal exposure)

Publication output has grown substantially over the last decade, rising from a handful of papers per year in 2017-2019 to a sustained higher rate of roughly 8-17 papers annually from 2021 onward.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 12.0/year recently
2017: 6 publications172018: 2 publications182019: 2 publications192020: 7 publications202021: 8 publications212022: 9 publications222023: 17 publications17232024: 8 publications242025: 14 publications252026: 12 publications26
Recent publications
Publishes in
  • bioRxiv (Cold Spring Harbor Laboratory)×15
  • Environmental Pollution×4
  • The Cambridge Structural Database×4
  • Alzheimer s & Dementia×4
  • Chemosphere×3
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This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 20, 2026.

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