LabCompass

Matthew Tegtmeyer

Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette

OpenAlex ORCID
Early career · publishing since 2019Rising activity
Single-cell and spatial transcriptomicsNeuroinflammation and Neurodegeneration MechanismsCRISPR and Genetic EngineeringNeuroscience and Neuropharmacology ResearchCell Image Analysis Techniques

Publications

36

Citations

738

Est. group size

~5

Recurring co-author estimate

Active years

8

Publishing since 2019

Research summary
AI-generated

Matthew Tegtmeyer studies how genetic variation affects brain cells, using stem-cell-derived neurons and astrocytes to model diseases such as Huntington's disease, Alzheimer's disease, schizophrenia, and 22q11.2 deletion syndrome. The work combines gene editing, single-cell genomics, and image-based cell profiling to link specific genes to changes in cell shape, molecular signatures, and disease-relevant behavior. Prospective students would likely engage with computational and wet-lab methods for studying human genetic risk factors in cellular disease models.

Stem-cell models of neurological and psychiatric diseaseGenetic risk variants and cellular phenotypesSingle-cell and spatial transcriptomicsAstrocyte-neuron interactionsCell image analysis and morphological profiling

Publication output has grown substantially over the last decade, rising from zero or minimal output before 2019 to a peak of around 9-10 papers per year in 2023 and 2025.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 6.2/year recently
17182019: 1 publication19202021: 4 publications212022: 4 publications222023: 9 publications232024: 6 publications242025: 10 publications10252026: 2 publications26
Recent publications
Publishes in
  • bioRxiv (Cold Spring Harbor Laboratory)×16
  • Nature Communications×3
  • European Neuropsychopharmacology×3
  • Cell×1
  • Cell stem cell×1
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This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 20, 2026.

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