M. T. Vu Hai
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
31
Citations
925
Est. group size
~2
Recurring co-author estimate
Active years
50
Publishing since 1977
M. T. Vu Hai's work focuses on pharmacokinetic and pharmacodynamic (PK/PD) modeling, which studies how drugs move through the body and how they produce their effects, to help predict and optimize drug dosing. Recent projects involve translating findings from lab/animal studies to first-in-human clinical trials for novel cancer drugs, modeling drug clearance and dosing in special populations such as older adults, and evaluating therapeutic drug monitoring approaches. This research supports the design of clinical trials and personalized dosing strategies across areas including oncology, cardiology, and transplant medicine.
Publication activity was minimal or absent for most of the past decade but increased sharply starting in 2023, with a noticeable rise in output through 2026.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Abstract CT118: Clinical pharmacokinetic and pharmacodynamic of JBZ-001 (HOSU-53): Comparison of first-in-human data with translational preclinical predictions
Cancer Research · 2026
- FcRn function alone cannot account for elevated IgG clearance in the Lewis lung carcinoma model of cancer cachexia
International Immunopharmacology · 2026
- Assessment of Therapeutic Drug Monitoring and Generalizability of a Population PK Model for Busulfan Applied across Five Datasets
2026
- Translational Pharmacokinetic-Pharmacodynamic Modeling of a Novel Oral Dihydroorotate Dehydrogenase (DHODH) Inhibitor, HOSU-53 (JBZ-001)
Pharmaceutics · 2025
- Modeling and inter-species scaling of plasma DHO as a biomarker to inform first-in-human dose selection for a novel DHODH inhibitor
2024
- Physiologically Based Pharmacokinetic Model for Older Adults and Its Application in Geriatric Drug Research
Current Drug Metabolism · 2023
- Model‐Informed Dosing Regimen of Ticagrelor in Chinese Patients With Acute Coronary Syndrome
Clinical Pharmacology & Therapeutics · 2023
- RAMP up: Risk Adapted Post-Autologous Transplant Maintenance Therapy in MRD Positive Myeloma Patients
Blood · 2023
- Current Drug Metabolism×1
- Pharmaceutics×1
- Clinical Pharmacology & Therapeutics×1
- Blood×1
- Cancers×1
- Sabbir Ahmed
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Heather L. Walker
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Hanieh Taheri
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Christopher C. Coss
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- James P. Sluka
Biochemistry, Genetics and Molecular Biology · Indiana University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
Claim or correct this profile