Christopher C. Coss
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
207
Citations
2,387
Est. group size
~44
Recurring co-author estimate
Active years
22
Publishing since 2005
Christopher C. Coss works on cancer biology and drug discovery, with a focus on hormone receptors (such as androgen and estrogen receptors) and how they drive cancers like prostate, hepatocellular, ovarian, and blood cancers (myeloma). His work spans identifying molecular targets of natural products and experimental drugs, testing new therapeutic compounds in lab models, and studying how hormone signaling and chromatin (DNA packaging) changes contribute to disease progression and treatment resistance.
Publication output has grown substantially over the last decade, rising from single digits annually before 2020 to over 40-50 outputs per year in 2023 and 2025, indicating an increasingly active and productive research program.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Natural Product Target Identification of Wheldone, a Fungal Metabolite, as a KIF11 Inhibitor in Ovarian Cancer Using the DiffPOP (Differential Protein Precipitation) Method
Molecular & Cellular Proteomics · 2026
- Abstract 6346: The chromatin remodeler SMARCA5 selectively shapes nuclear receptor signaling in African American prostate cancer
Cancer Research · 2025
- Dual Treatment of a Beta 3 Adrenergic Receptor Agonist and a Novel Estrogen Receptor Beta Agonist on Body Composition, Metabolism, and Glucose Tolerance in Obese Male Mice
Physiology · 2025
- Androgens Drive SOX9 Upregulation in Injured Proximal Tubular Cells
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- Triptolide and its prodrug Minnelide target high-risk MYC-amplified medulloblastoma in preclinical models
Journal of Clinical Investigation · 2024
- Merging Natural Product Structures with Pharmaceutical Leads: Unnatural Enantiomers of Estranes as Glucocorticoid Receptor Modulators That Suppress TNF-α and IL-6 Release
Journal of Medicinal Chemistry · 2024
- Exploration of Verticillins in High-Grade Serous Ovarian Cancer and Evaluation of Multiple Formulations in Preclinical In Vitro and In Vivo Models
Molecular Pharmaceutics · 2023
- Data from Molecular Target Characterization and Antimyeloma Activity of the Novel, Insulin-like Growth Factor 1 Receptor Inhibitor, GTx-134
2023
- Data from Novel Selective Agents for the Degradation of Androgen Receptor Variants to Treat Castration-Resistant Prostate Cancer
2023
- Data from Transcriptionally Active Androgen Receptor Splice Variants Promote Hepatocellular Carcinoma Progression
2023
- Data from Transcriptionally Active Androgen Receptor Splice Variants Promote Hepatocellular Carcinoma Progression
2023
- Supporting Figures S5-S8 from Novel Selective Agents for the Degradation of Androgen Receptor Variants to Treat Castration-Resistant Prostate Cancer
2023
- Supporting figure legends and methods from Novel Selective Agents for the Degradation of Androgen Receptor Variants to Treat Castration-Resistant Prostate Cancer
2023
- Supporting Figures S1-S4 from Novel Selective Agents for the Degradation of Androgen Receptor Variants to Treat Castration-Resistant Prostate Cancer
2023
- Supplementary methods from Transcriptionally Active Androgen Receptor Splice Variants Promote Hepatocellular Carcinoma Progression
2023
- Cancer Research×12
- bioRxiv (Cold Spring Harbor Laboratory)×6
- Regular and Young Investigator Award Abstracts×6
- Journal of Clinical Oncology×4
- Clinical Cancer Research×3
- Omar Khalid
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Heather L. Walker
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Hedieh Jafari
Medicine · The Ohio State University
- Hanieh Taheri
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- James P. Sluka
Biochemistry, Genetics and Molecular Biology · Indiana University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
Claim or correct this profile