Kyle A. Cottrell
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
Publications
79
Citations
644
Est. group size
~4
Recurring co-author estimate
Active years
15
Publishing since 2011
Kyle A. Cottrell studies how cells sense and respond to double-stranded RNA, with a particular focus on an RNA-editing enzyme called ADAR1 and its role in cancer, especially triple-negative breast cancer. His work also touches on how cells translate mRNA into protein and how RNA molecules are packaged and transferred between cells via extracellular vesicles. This research could interest students wanting to explore RNA biology, gene regulation, and mechanisms underlying cancer cell survival.
Publication output was low and steady through the mid-2010s to early 2020s, then increased sharply in 2024, suggesting a recent surge in research activity.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- ZYS-1 is not an ADAR1 inhibitor
RNA · 2025
- Proteomic Tracking Extracellular Vesicle RNA Interactors in Recipient Immune Cells through Orthogonal Labelings
Journal of the American Chemical Society · 2025
- ADAR1 Regulates Lipid Remodeling to Dictate Ferroptosis Sensitivity
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- Abstract 1635 Evaluating the role of RIG-I in Triple-Negative Breast Cancer
Journal of Biological Chemistry · 2025
- ZYS-1 is not an ADAR1 inhibitor
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- The competitive landscape of the dsRNA world
Molecular Cell · 2023
- Induction of viral mimicry upon loss of DHX9 and ADAR1 in breast cancer cells
bioRxiv (Cold Spring Harbor Laboratory) · 2023
- Induction of Viral Mimicry Upon Loss of Dhx9 and Adar1 in Breast Cancer Cells
SSRN Electronic Journal · 2023
- Abstract IA012: Reducing disparities in breast cancer mortality through the identification of novel targets in triple-negative breast cancer
Cancer Epidemiology Biomarkers & Prevention · 2023
- Abstract 876: Proximity labeling reveals a role for ADAR and DDX54 in suppressing dsRNA sensing in breast cancer
Cancer Research · 2022
- Abstract 842: ADAR and DDX54 promote genomic stability in breast cancer cells
Cancer Research · 2022
- 8-Azaadenosine and 8-Chloroadenosine are not Selective Inhibitors of ADAR
Cancer Research Communications · 2021
- Correction to: Evaluating the therapeutic potential of ADAR1 inhibition for triple-negative breast cancer
Oncogene · 2021
- 8-azaadenosine and 8-chloroadenosine are not selective inhibitors of ADAR
bioRxiv (Cold Spring Harbor Laboratory) · 2021
- Evaluating the therapeutic potential of ADAR1 inhibition for triple-negative breast cancer
Oncogene · 2020
- bioRxiv (Cold Spring Harbor Laboratory)×9
- Scientific Reports×3
- Nature Communications×2
- Oncogene×2
- Cancer Research Communications×2
- Jackson R. Pierce
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Heather A. Hundley
Biochemistry, Genetics and Molecular Biology · Indiana University
- Suba Rajendren
Biochemistry, Genetics and Molecular Biology · Indiana University
- Jered Myslinski
Biochemistry, Genetics and Molecular Biology · Indiana University
- Zan Xu
Biochemistry, Genetics and Molecular Biology · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 20, 2026.
Claim or correct this profile