LabCompass

Jackson R. Pierce

Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette

OpenAlex ORCID
Established · publishing since 1981Rising activity
RNA regulation and diseaseVirus-based gene therapy researchViral Infections and Immunology ResearchRNA Interference and Gene DeliveryMicroRNA in disease regulation

Publications

56

Citations

83

Est. group size

~3

Recurring co-author estimate

Active years

45

Publishing since 1981

Research summary
AI-generated

Jackson R. Pierce studies how cells sense double-stranded RNA (a molecular signal that can trigger immune-like alarm responses) and how cancer cells, particularly breast cancer cells, suppress or exploit this sensing system. Recent work focuses on proteins like PKR, PACT, DHX9, and ADAR1, which regulate RNA-triggered immune responses, and explores how disrupting these proteins might be used as a cancer therapy strategy. This research sits at the intersection of RNA biology, cancer biology, and innate immune signaling.

Double-stranded RNA sensingPKR/PACT signaling pathwaysRNA editing and viral mimicry (ADAR1, DHX9)Breast cancer molecular biologyRNA-based therapeutic targets

Publication records show no listed output from 2017-2023 followed by a sharp concentration of activity in 2024, suggesting either a recent surge in output or a gap in earlier indexed records rather than a steady long-term trend.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 10.8/year recently
171819202122232024: 52 publications52242025: 2 publications2526
Recent publications
Publishes in
  • bioRxiv (Cold Spring Harbor Laboratory)×2
  • Cancer Research Communications×1
  • Biochemical Society Transactions×1
  • RNA×1
  • Scientific Reports×1
Similar researchers
By research-topic overlap
  • Kyle A. Cottrell

    Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette

  • Zan Xu

    Biochemistry, Genetics and Molecular Biology · The Ohio State University

  • Jered Myslinski

    Biochemistry, Genetics and Molecular Biology · Indiana University

  • Heather A. Hundley

    Biochemistry, Genetics and Molecular Biology · Indiana University

  • Emily A. Erdmann

    Biochemistry, Genetics and Molecular Biology · Indiana University

This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 20, 2026.

Claim or correct this profile