Jay L. Zweíer
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
754
Citations
52,719
Est. group size
~10
Recurring co-author estimate
Active years
50
Publishing since 1977
This researcher studies how heart tissue is damaged and protected during heart attacks and the restoration of blood flow afterward (ischemia and reperfusion injury), with a focus on oxidative stress, nitric oxide signaling, and mitochondrial function. The work combines cardiovascular biology with specialized imaging methods, particularly electron spin resonance (EPR) and MRI, to detect free radicals and tissue damage. Additional projects examine effects of cigarette and e-cigarette smoke exposure on blood vessels and lungs.
Publication output has declined over the last decade, from around 16 papers per year in 2017 to roughly 4-7 per year in recent years.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- <b>CARDIAC ISCHEMIA AND REPERFUSION</b>
2025
- High fidelity triangular sweep of the magnetic field for millisecond scan EPR imaging
Journal of Magnetic Resonance · 2021
- Reperfusion mediates heme impairment with increased protein cysteine sulfonation of mitochondrial complex III in the post-ischemic heart
Journal of Molecular and Cellular Cardiology · 2021
- Serine mutations in overexpressed Hsp27 abrogate the protection against doxorubicin-induced p53-dependent cardiac apoptosis in mice
American Journal of Physiology-Heart and Circulatory Physiology · 2021
- Development of an L‐band resonator optimized for fast scan EPR imaging of the mouse head
Magnetic Resonance in Medicine · 2021
- Evaluation of Fast Scan EPR for High-Resolution Imaging Using Nitroxide Radical Probes at 1.2 GHz
Applied Magnetic Resonance · 2021
- Imbalance in zinc homeostasis enhances lung Tissue Loss following cigarette smoke exposure
Journal of Trace Elements in Medicine and Biology · 2020
- Whole body electronic cigarette exposure system for efficient evaluation of diverse inhalation conditions and products
Inhalation Toxicology · 2020
- Dioxygen Binding and Sensing Proteins
Antioxidants and Redox Signaling · 2020
- Abstract 40: Time Course of Cerebral Small Vessel Disease Lesions and Sensory Motor Changes in Spontaneously Hypertensive Stroke Prone Rats
Stroke · 2020
- Inhibition of CD38 with the Thiazoloquin(az)olin(on)e 78c Protects the Heart against Postischemic Injury
Journal of Pharmacology and Experimental Therapeutics · 2019
- Regulation of Nitric Oxide Metabolism and Vascular Tone by Cytoglobin
Antioxidants and Redox Signaling · 2019
- Genetic Differences in Phenytoin PharmacokineticsIn vivo Clearance andin vitro Metabolism among Inbred Strains of Mice
Developmental Pharmacology and Therapeutics · 2019
- Abstract 14532: Serine Mutations in Hsp27 Abrogate Its Ability to Inhibit p53 Dependent Apoptosis and Doxorubicin-Induced Heart Failure in Mice
Circulation · 2019
- Mitochondrial complex I in the post-ischemic heart: reperfusion-mediated oxidative injury and protein cysteine sulfonation
Journal of Molecular and Cellular Cardiology · 2018
- Stroke×17
- The FASEB Journal×10
- American Journal of Physiology-Heart and Circulatory Physiology×4
- Circulation×4
- Journal of Molecular and Cellular Cardiology×3
- Lawrence J. Berliner
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Frederick A. Villamena
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- A. M. Wasserman
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Bhavani Gopalakrishnan
Medicine · Purdue University West Lafayette
- Yong Xia
Medicine · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
Claim or correct this profile