Frederick A. Villamena
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
131
Citations
5,405
Est. group size
—
Recurring co-author estimate
Active years
28
Publishing since 1998
Frederick A. Villamena's research focuses on developing chemical tools and probes to detect and study reactive molecules (like free radicals and reactive oxygen species) in biological systems, using a technique called electron paramagnetic resonance (EPR) spectroscopy. This work involves designing new molecules, such as nitrones and trityl radicals, that can trap or react with unstable chemical species to reveal information about oxidative stress and cellular chemistry relevant to health and disease.
Publication output was higher and more frequent between 2017 and 2020 (up to 7 papers in 2018) but has slowed considerably since 2021, averaging about 1 publication per year over the last five years.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- <b>CHEMISTRY OF REACTIVE SPECIES</b>
2025
- Trityl Quinodimethane Derivatives as Unimolecular Triple-Function Extracellular EPR Probes for Redox, pH, and Oxygen
Analytical Chemistry · 2023
- Substituted α-Phenyl and α-Naphthlyl-<i>N</i>-<i>tert</i>-butyl Nitrones: Synthesis, Spin-Trapping, and Neuroprotection Evaluation
The Journal of Organic Chemistry · 2020
- Clinical Probes for ROS and Oxidative Stress
Biological magnetic resonance · 2020
- Discriminative Detection of Biothiols by Electron Paramagnetic Resonance Spectroscopy using a Methanethiosulfonate Trityl Probe
Angewandte Chemie International Edition · 2019
- Discriminative Detection of Biothiols by Electron Paramagnetic Resonance Spectroscopy using a Methanethiosulfonate Trityl Probe
Angewandte Chemie · 2019
- Nutritional Ketosis and Mitohormesis: Potential Implications for Mitochondrial Function and Human Health
Journal of Nutrition and Metabolism · 2018
- Synthesis and Characterization of the Perthiatriarylmethyl Radical and Its Dendritic Derivatives with High Sensitivity and Selectivity to Superoxide Radical
Chemistry - A European Journal · 2018
- Co-ingestion of whole eggs or egg whites with glucose protects against postprandial hyperglycaemia-induced oxidative stress and dysregulated arginine metabolism in association with improved vascular endothelial function in prediabetic men
British Journal Of Nutrition · 2018
- Synthesis and Characterization of the Perthiatriarylmethyl Radical and Its Dendritic Derivatives with High Sensitivity and Selectivity to Superoxide Radical
Chemistry - A European Journal · 2018
- Front Cover: Synthesis and Characterization of the Perthiatriarylmethyl Radical and Its Dendritic Derivatives with High Sensitivity and Selectivity to Superoxide Radical (Chem. Eur. J. 27/2018)
Chemistry - A European Journal · 2018
- Thiol-Dependent Reduction of the Triester and Triamide Derivatives of Finland Trityl Radical Triggers O<sub>2</sub>-Dependent Superoxide Production
Chemical Research in Toxicology · 2017
- Biocompatibility and antibacterial activity of nitrogen-doped titanium dioxide nanoparticles for use in dental resin formulations
International Journal of Nanomedicine · 2016
- EPR Spin Trapping
Elsevier eBooks · 2016
- Synthesis and Characterization of PEGylated Trityl Radicals: Effect of PEGylation on Physicochemical Properties
The Journal of Organic Chemistry · 2016
- Elsevier eBooks×8
- Chemistry - A European Journal×3
- Environmental Science & Technology×2
- The Journal of Organic Chemistry×2
- The Journal of Nutritional Biochemistry×2
- Jay L. Zweíer
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Lawrence J. Berliner
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- A. M. Wasserman
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Yuheng Huang
Materials Science · Indiana University
- Roxanna Martinez
Materials Science · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
Claim or correct this profile