Isabelle Deschênes

Isabelle Deschênes studies how heart cells generate electrical signals, focusing on cardiac ion channels—proteins that control the flow of charged particles (like sodium and chloride) across cell membranes to produce heartbeats. Her work examines how mutations and regulatory proteins affect these channels, using techniques such as patient-derived stem cell models, structural biology, and electrophysiology (measurement of electrical activity in cells) to understand and potentially treat heart rhythm disorders like long QT syndrome and Brugada syndrome.

Publication output has fluctuated over the past decade, with a peak around 2017-2018, a dip in 2019-2020, and a partial recovery to a moderate, steady pace of roughly 6-12 papers per year in recent years.

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