Publications
22
Citations
402
Est. group size
~1
Recurring co-author estimate
Active years
11
Publishing since 2016
Hsi-Chun Chao's research focuses on developing and applying mass spectrometry techniques, especially gas-phase ion/ion chemistry methods, to study complex lipids such as sphingolipids, glycosphingolipids, phosphoinositides, and gangliosides. This work aims to distinguish structurally similar lipid variants (isomers) and quantify them in biological samples like brain tissue and blood, with applications to understanding disease processes such as stroke and neurodegeneration.
Publication output has been variable over the past decade, with active years (e.g., 2017, 2020-2022) interspersed with gaps (2018, 2023-2024), and a recent resurgence in 2025-2026.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- A Brugada-related KCNT1 mutation unveils its conductance-independent activation of store-operated Ca <sup>2+</sup> entry
bioRxiv (Cold Spring Harbor Laboratory) · 2026
- Isomer-Resolved Mass Spectrometry Imaging Reveals Regional and Age-Dependent Glycolipid Metabolism in Rat Brain
ACS Central Science · 2026
- Isomer-ResolvedMass Spectrometry Imaging RevealsRegional and Age-Dependent Glycolipid Metabolism in Rat Brain
Figshare · 2026
- Precursor Resolution via Ion Z‐State Manipulation: A Tandem Mass Spectrometry Approach for the Analysis of Mixtures of Multiply‐Charged Ions
Journal of Mass Spectrometry · 2025
- Altering Lipid A Precursor Ion Types in the Gas Phase for In-Depth Structural Elucidation via Tandem Mass Spectrometry
Analytical Chemistry · 2025
- Adaptation and operation of a quadrupole/time-of-flight tandem mass spectrometer for high mass ion/ion reaction studies
International Journal of Mass Spectrometry · 2022
- Structural elucidation and isomeric differentiation/quantitation of monophosphorylated phosphoinositides using gas-phase ion/ion reactions and dissociation kinetics
The Analyst · 2022
- Recent advances in gas-phase ion/ion chemistry for lipid analysis
TrAC Trends in Analytical Chemistry · 2022
- Characterization of Homopolymer Distributions via Direct Infusion ESI-MS/MS using Wide Mass-to-Charge Windows and Gas-Phase Ion/Ion Reactions
Journal of the American Society for Mass Spectrometry · 2022
- Plasma ceramides are associated with outcomes in acute ischemic stroke patients
Journal of the Formosan Medical Association · 2021
- In-Depth Structural Characterization and Quantification of Cerebrosides and Glycosphingosines with Gas-Phase Ion Chemistry
Analytical Chemistry · 2021
- Manipulation of Ion Types via Gas-Phase Ion/Ion Chemistry for the Structural Characterization of the Glycan Moiety on Gangliosides
Analytical Chemistry · 2021
- Using the PCI-IS Method to Simultaneously Estimate Blood Volume and Quantify Nonvitamin K Antagonist Oral Anticoagulant Concentrations in Dried Blood Spots
Analytical Chemistry · 2020
- Differentiation and Quantification of Diastereomeric Pairs of Glycosphingolipids Using Gas-Phase Ion Chemistry
Analytical Chemistry · 2020
- Generation of Multiply Charged Protein Anions from Multiply Charged Protein Cations via Gas-Phase Ion/Ion Reactions
Journal of the American Society for Mass Spectrometry · 2020
- Analytical Chemistry×5
- Journal of Chromatography A×2
- Journal of the American Society for Mass Spectrometry×2
- International Journal of Mass Spectrometry×1
- EMBO Reports×1
- Kimberly C. Fabijanczuk
Chemistry · Purdue University West Lafayette
- Michael T. Marty
Chemistry · Indiana University
- J. E. Hallett
Chemistry · Purdue University West Lafayette
- Daisy Unsihuay
Chemistry · Purdue University West Lafayette
- Alexander J. Grooms
Chemistry · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 20, 2026.
Claim or correct this profile