Guy M. Lenk
Biochemistry, Genetics and Molecular Biology · University of Michigan
Publications
56
Citations
3,639
Est. group size
~2
Recurring co-author estimate
Active years
22
Publishing since 2005
Typically publishes in teams of ~11 · 10% small-team papers (≤3 authors) · across 15 venues
- Early-onset neuroinflammation drives neurodegeneration caused by lysosomal PI(3,5)P2 insufficiency
Neurobiology of Disease · 2026
- Biallelic loss-of-function variants of SLC12A9 cause lysosome dysfunction and a syndromic neurodevelopmental disorder
Genetics in Medicine · 2024
- Protein family FAM241 in human and mouse
Mammalian Genome · 2024
- 110VP FIG4 loss of function: Unraveling the phenotypic spectrum for clinical trial readiness
Neuromuscular Disorders · 2024
- The chloride antiporter CLCN7 is a modifier of lysosome dysfunction in FIG4 and VAC14 mutants
PLoS Genetics · 2023
- Altered phenotypes due to genetic interaction between the mouse phosphoinositide biosynthesis genes <i>Fig4</i> and <i>Pip4k2c</i>
G3 Genes Genomes Genetics · 2023
- Lysosome enlargement during inhibition of the lipid kinase PIKfyve proceeds through lysosome coalescence
2023
- Lysosome enlargement during inhibition of the lipid kinase PIKfyve proceeds through lysosome coalescence
2023
- Chloroquine corrects enlarged lysosomes in FIG4 null cells and reduces neurodegeneration in Fig4 null mice
Molecular Genetics and Metabolism · 2022
- AAV9-mediated FIG4 delivery prolongs life span in Charcot-Marie-Tooth disease type 4J mouse model
Journal of Clinical Investigation · 2021
- CRISPR knockout screen implicates three genes in lysosome function
Scientific Reports · 2019
- PIKfyve complex regulates early melanosome homeostasis required for physiological amyloid formation
Journal of Cell Science · 2019
- Cerebral hypomyelination associated with biallelic variants of <i>FIG4</i>
Human Mutation · 2019
- VAC14 Gene‐Related Parkinsonism‐Dystonia With Response to Deep Brain Stimulation
Movement Disorders Clinical Practice · 2019
- Correction: The PIKfyve complex regulates the early melanosome homeostasis required for physiological amyloid formation (doi:10.1242/jcs.229500)
Journal of Cell Science · 2019
- Journal of Cell Science×3
- bioRxiv (Cold Spring Harbor Laboratory)×2
- Annals of Neurology×1
- The American Journal of Human Genetics×1
- Scientific Reports×1
- Xiaoyan Zhang
Biochemistry, Genetics and Molecular Biology · University of Michigan
- Lois S. Weisman
Biochemistry, Genetics and Molecular Biology · University of Michigan
- Felichi Mae Arines
Biochemistry, Genetics and Molecular Biology · University of Michigan
- Pilar Rivero-Ríos
Biochemistry, Genetics and Molecular Biology · University of Michigan
- Natsuko Jin
Biochemistry, Genetics and Molecular Biology · University of Michigan
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 25, 2026.
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