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Diana R. Tomchick

Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette

OpenAlex ORCID
Established · publishing since 1987
Biochemical and Molecular ResearchEnzyme Structure and FunctionCellular transport and secretionSyphilis Diagnosis and TreatmentAmino Acid Enzymes and Metabolism

Publications

269

Citations

13,145

Est. group size

—

Recurring co-author estimate

Active years

40

Publishing since 1987

Research summary
AI-generated

Diana R. Tomchick works on determining the three-dimensional structures of proteins and enzymes to understand how they function and malfunction in disease, using techniques such as X-ray crystallography. Her collaborative work spans diverse biological problems, including bacterial immune systems, metabolic and lipid-related genetic disorders, cell signaling proteins, and drug target discovery for conditions like malaria and heart disease. This structural biology expertise is applied across many collaborative projects with other labs studying specific diseases and biological pathways.

Protein structure determination (X-ray crystallography)Metabolic and lipid disorder geneticsEnzyme mechanism and drug target discoveryBacterial and host-pathogen molecular interactionsCell signaling protein structures

Publication output has fluctuated over the last decade, with a peak in 2020, a marked slowdown between 2021-2023, and a partial rebound in 2024-2025.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 5.4/year recently
2017: 12 publications172018: 13 publications182019: 10 publications192020: 20 publications20202021: 5 publications212022: 3 publications222023: 2 publications232024: 13 publications242025: 7 publications252026: 2 publications26
Recent publications
Publishes in
  • bioRxiv (Cold Spring Harbor Laboratory)×10
  • Acta Crystallographica Section A Foundations and Advances×8
  • Proceedings of the National Academy of Sciences×6
  • eLife×5
  • Journal of Biological Chemistry×5
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This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 20, 2026.

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