Dehua Pei

Dehua Pei's research focuses on how peptides and proteins can be engineered to cross cell membranes and reach targets inside cells, a major challenge for developing drugs that act on intracellular processes. The group designs cyclic and bicyclic peptides, cell-penetrating peptide motifs, and related delivery strategies, and applies these tools to disrupt protein-protein interactions relevant to disease, such as those involving Gαi/s proteins and STAT6.

Publication output has been fairly steady but has gradually declined over the past decade, from around 7-9 papers per year in 2017-2020 to roughly 3-7 per year in recent years.

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