Alan D. Palkowitz
Biochemistry, Genetics and Molecular Biology · Indiana University
Publications
57
Citations
2,012
Est. group size
—
Recurring co-author estimate
Active years
42
Publishing since 1985
Alan D. Palkowitz works on discovering and developing new drug candidates for Alzheimer's disease, with a focus on identifying and validating biological targets and designing chemical compounds (ligands) that act on them. Much of this work is conducted through the Indiana University School of Medicine\u2013Purdue University TREAT-AD Center, part of a national consortium building 'target enablement' resources to support next-generation Alzheimer's therapeutics. The research combines medicinal chemistry, cell-based models, and immune-focused signaling pathways relevant to the disease.
After several years with no recorded output, publication activity has been steady with a recent increase, peaking in 2026.
Generated by claude-opus-4-8 from public bibliographic data · Jul 9, 2026
Current awards run through December 2029 — about 3 years of funding on record from today. Awards are often renewed, so this is what is currently public, not a forecast.
Optimization of SHIP1 Inhibitors for the Treatment of Alzheimer's Disease
Admin-Core
Matched to public NIH RePORTER and NSF records by name and institution. Awards from other agencies are not shown, and a match is not always found — this list may be incomplete.
Typically publishes in teams of ~14 · 0% small-team papers (≤3 authors) · across 6 venues
- Optimization and Characterization of SHIP1 Ligands for Cellular Target Engagement and Activity in Alzheimer’s Disease Models
Journal of Medicinal Chemistry · 2026
- Next‐generation Alzheimer's therapeutics: target assessment and enablement at the Indiana University School of Medicine–Purdue University TREAT‐AD Center
Alzheimer s & Dementia · 2026
- From consortia discovery to biotech creation: An innovative approach to next‐gen Alzheimer's drugs
Alzheimer s & Dementia · 2026
- Optimization and Characterization of SHIP1 Ligands for Cellular Target Engagement and Activity in Alzheimer’s Disease Models
bioRxiv (Cold Spring Harbor Laboratory) · 2026
- Generation and characterization of iPSC‐derived microglia for in vitro modeling of stimuli‐specific neuroimmune responses
Alzheimer s & Dementia · 2026
- Evaluation of ASC as a therapeutic target for Alzheimer's disease
Alzheimer s & Dementia · 2026
- Identification of PLCγ2 activators for the treatment of Alzheimer’s disease
Alzheimer s & Dementia · 2025
- IUSM‐Purdue TREAT‐AD Center Capabilities and Strategy to Enable and Advance Novel Therapeutic Targets for the Treatment of Alzheimer’s Disease
Alzheimer s & Dementia · 2024
- Identification of PLCG2 activators for the treatment of Alzheimer’s disease
Alzheimer s & Dementia · 2024
- Generation and validation of anti‐TREM2 agonistic antibodies to enable the advancement of drug targets in the TREM2/DAP12 signaling pathway for the treatment of Alzheimer Disease
Alzheimer s & Dementia · 2024
- SHIP1 therapeutic target enablement: Identification and evaluation of inhibitors for the treatment of late‐onset Alzheimer's disease
Alzheimer s & Dementia Translational Research & Clinical Interventions · 2023
- A target enablement package for modulating the activity of PLCγ2 as a therapeutic strategy for the treatment of Alzheimer’s disease
Alzheimer s & Dementia · 2023
- IUSM-Purdue TREAT-AD Center Target Enabling Package; INPP5D (SHIP1)
Zenodo (CERN European Organization for Nuclear Research) · 2022
- A Target Enablement Package for the Inhibition of SHIP1 as a Therapeutic Strategy for the Treatment of Alzheimer’s Disease
Alzheimer s & Dementia · 2022
- Role of Animal Models in Alzheimer’s Disease Drug Development
Cambridge University Press eBooks · 2022
- Alzheimer s & Dementia×12
- Zenodo (CERN European Organization for Nuclear Research)×2
- Alzheimer s & Dementia Translational Research & Clinical Interventions×1
- Cambridge University Press eBooks×1
- bioRxiv (Cold Spring Harbor Laboratory)×1
- Andrew McGrath
Biochemistry, Genetics and Molecular Biology · University of Michigan
- Tim Cernak
Biochemistry, Genetics and Molecular Biology · University of Michigan
- Zirong Zhang
Biochemistry, Genetics and Molecular Biology · University of Michigan
- Shen Wang
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Abdulkhaliq A. Alawaed
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 27, 2026.
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