David E. Symer
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
139
Citations
4,091
Est. group size
~2
Recurring co-author estimate
Active years
43
Publishing since 1984
David E. Symer's research centers on understanding the molecular and cellular biology of multiple myeloma, a cancer of plasma cells in bone marrow, using single-cell and molecular profiling techniques to identify new disease mechanisms and treatment targets. Earlier work also examined human papillomavirus (HPV)-related cancers and the behavior of mobile genetic elements (retrotransposons) in the genome. The lab uses approaches like single-cell RNA sequencing, proteomics, and liquid biopsy methods to study how cancer cells evolve and resist treatment.
Publication output was relatively low and steady from 2017–2022 but increased sharply in 2023 and 2025, suggesting a recent surge in research activity or collaborative output.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Targeting caseinolytic mitochondrial matrix peptidase, a novel contributor to the pathobiology of high-risk multiple myeloma
Blood · 2025
- Single-cell analysis of neoplastic plasma cells identifies myeloma pathobiology mediators and potential targets
Cell Reports Medicine · 2025
- Single cell clonotypic and transcriptional evolution of multiple myeloma precursor disease
Cancer Cell · 2023
- Targeted single-cell proteomic analysis identifies new liquid biopsy biomarkers associated with multiple myeloma
npj Precision Oncology · 2023
- Caseinolytic Mitochondrial Matrix Peptidase Proteolytic Subunit (CLPP) As a Novel Mediator of, and Target in High Risk Multiple Myeloma
Blood · 2023
- Lysosomal Associated Membrane Protein Family Member 5 (LAMP5) As a Novel Mediator of, and Target in High Risk Multiple Myeloma (MM)
Blood · 2023
- CCR Translation on the Article from Oral Human Papillomavirus Infection Before and After Treatment for Human Papillomavirus 16–Positive and Human Papillomavirus 16–Negative Head and Neck Squamous Cell Carcinoma
2023
- Data from Oral Human Papillomavirus Infection Before and After Treatment for Human Papillomavirus 16–Positive and Human Papillomavirus 16–Negative Head and Neck Squamous Cell Carcinoma
2023
- Data from Oral Human Papillomavirus Infection Before and After Treatment for Human Papillomavirus 16–Positive and Human Papillomavirus 16–Negative Head and Neck Squamous Cell Carcinoma
2023
- CCR Translation on the Article from Oral Human Papillomavirus Infection Before and After Treatment for Human Papillomavirus 16–Positive and Human Papillomavirus 16–Negative Head and Neck Squamous Cell Carcinoma
2023
- Single Cell Multi-Omic Analysis of Neoplastic Plasma Cells across the Disease Spectrum Identifies Novel Pathobiologic Mediators and Potential Therapeutic Targets in Multiple Myeloma (MM)
Blood · 2023
- Enrichment-Free Single-Cell Detection and Morphogenomic Profiling of Myeloma Patient Samples to Delineate Circulating Rare Plasma Cell Clones
Current Oncology · 2022
- Single Cell Clonotypic and Transcriptional Evolution of Multiple Myeloma Precursor Disease
SSRN Electronic Journal · 2022
- Single Cell Profiling of BCMA Naïve Vs Refractory Relapsed Myeloma Patients Reveals Unique Transcriptomic Profiles in Tumor and Microenvironment
Blood · 2022
- HPV positive neuroendocrine cervical cancer cells are dependent on Myc but not E6/E7 viral oncogenes
Scientific Reports · 2017
- Figshare×7
- Blood×5
- bioRxiv (Cold Spring Harbor Laboratory)×3
- Cancer Discovery×2
- Genome Research×2
- Keiko Akagi
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Richard K. Wilson
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Julie Martin
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- S. Cenk Şahinalp
Biochemistry, Genetics and Molecular Biology · Indiana University
- Anoosha Paruchuri
Biochemistry, Genetics and Molecular Biology · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
Claim or correct this profile