Anoosha Paruchuri

Biochemistry, Genetics and Molecular Biology · The Ohio State University

Mid career · publishing since 2016Rising activity

Cancer Genomics and Diagnostics Fibroblast Growth Factor Research Cholangiocarcinoma and Gallbladder Cancer Studies Pancreatic and Hepatic Oncology Research Ferroptosis and cancer prognosis

Publications

Citations

185

Est. group size

~12

Recurring co-author estimate

Active years

Publishing since 2016

Research summary

AI-generated

Anoosha Paruchuri's research focuses on understanding cancer at the molecular level, particularly how gene mutations drive tumor development versus which mutations are incidental byproducts. The work combines computational approaches like machine learning and molecular modeling with laboratory validation to study cancer-related genes, regulatory DNA elements, and potential drug-binding sites, spanning cancers such as melanoma, breast cancer, and lung cancer (via EGFR).

Cancer driver mutation identificationComputational and machine-learning methods in cancer researchGene regulation and epigenetics in cancerDrug target and binding site predictionMolecular modeling of cancer therapeutics

Publication output has been variable but sustained over the last decade, with a notable early peak in 2019, a dip afterward, and a renewed increase in output from 2023 through 2026.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence

Publications per year over the last 10 years — averaging 3.2/year recently

Recent publications

Classification of driver and passenger mutations in different cancer types using deep neural networks
Bioinformatics Advances · 2026
Multi-Scale Computational Investigation of Heliotropium indicum Phytochemicals as Multi-Target Therapeutics Against Breast Cancer: Integration of Network Pharmacology, Molecular Dynamics with Free- Energy Calculation, and Machine Learning
Research Square · 2026
ML-Based Classification of Druggable Binding Sites Integrating AlphaFold Confidence Metrics
Research Square · 2026
<i>In Vitro</i> Validation of Computationally Predicted Oncogenic Driver Mutations in EGFR Tyrosine Kinase Domain
bioRxiv (Cold Spring Harbor Laboratory) · 2023
PPAR-Responsive Elements Enriched with Alu Repeats May Contribute to Distinctive PPARγ–DNMT1 Interactions in the Genome
Cancers · 2021
Mutational Landscape of the BAP1 Locus Reveals an Intrinsic Control to Regulate the miRNA Network and the Binding of Protein Complexes in Uveal Melanoma
Cancers · 2019
Exploring preferred amino acid mutations in cancer and discrimination of driver and passenger mutations in epidermal growth factor receptor
Faculty of 1000 Research Ltd · 2016

Publishes in

Cancer Research×5
Cancers×2
JCO Precision Oncology×2
Journal of Clinical Oncology×2
medRxiv×2

Similar researchers

By research-topic overlap

Zachary Risch
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Sameek Roychowdhury
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Julie W. Reeser
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Michele R. Wing
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Karan Rai
Biochemistry, Genetics and Molecular Biology · The Ohio State University

This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 19, 2026.

Claim or correct this profile