Christine S. Muli
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
Publications
26
Citations
304
Est. group size
~5
Recurring co-author estimate
Active years
12
Publishing since 2014
Christine S. Muli's work spans biochemistry and drug discovery, including studies of protein degradation pathways (like the ubiquitin-proteasome system, which cells use to break down unwanted proteins), structural biology methods such as NMR and crystallography, and the design of small-molecule inhibitors targeting cancer-related proteins like RAF kinases. Recent publications also touch on synthetic chemistry, such as sugar-based surfactant molecules. This research combines chemical synthesis, structural analysis, and biological testing to understand and potentially treat disease-related protein malfunctions, particularly in cancer.
Publication output has grown notably in recent years, rising from occasional single papers in 2017-2020 to a higher and increasing yearly count from 2023 through 2025.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- NMR in the Age of Modern Biomedical Research and Drug Discovery
Journal of Molecular Biology · 2025
- High-throughput assay exploiting disorder-to-order conformational switches: application to the proteasomal Rpn10:E6AP complex
Chemical Science · 2024
- Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a 5-Fluoro-4-(3 <i>H</i> )-quinazolinone Aryl Urea pan-RAF Kinase Inhibitor
Journal of Medicinal Chemistry · 2021
- Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a Pyridopyridazinone pan-RAF Kinase Inhibitor
ACS Medicinal Chemistry Letters · 2021
- CCDC 2076522: Experimental Crystal Structure Determination
The Cambridge Structural Database · 2021
- CCDC 2076521: Experimental Crystal Structure Determination
The Cambridge Structural Database · 2021
- The Physico-Chemical Properties of Sugar-Oxime-Ether Surfactants
Tenside Surfactants Detergents · 2020
- Journal of Medicinal Chemistry×3
- Bioorganic & Medicinal Chemistry Letters×3
- Scientific Reports×2
- ChemBioChem×2
- The Cambridge Structural Database×2
- Darci J. Trader
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Rishi Patel
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Joseph Mills
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Cody A. Loy
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Kankan Wang
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 20, 2026.
Claim or correct this profile