Chen Gu
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
43
Citations
1,554
Est. group size
~3
Recurring co-author estimate
Active years
26
Publishing since 2001
Chen Gu studies how neurons organize their internal skeleton (cytoskeleton) and membrane proteins, particularly ion channels, to support normal brain function and how this goes wrong in disease. Work spans mechanisms of axon injury from mechanical forces, myelin regulation, and how mislocalized ion channels contribute to conditions like spinocerebellar ataxia and schizophrenia. Much of the research uses cell biology and neuroscience techniques to link molecular-level cytoskeleton-membrane interactions to behaviors such as movement, emotion, and memory.
Publication output has been modest and fluctuating over the last decade, dipping to zero in 2020 and generally averaging under two papers per year in the most recent five years, though with a slight uptick in 2025.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Proper localization of the SCA13-linked K+ channel in Purkinje neurons requires a microtubule-stabilizing protein
Neurobiology of Disease · 2026
- Blocking axon-glial mechanotransduction to prevent concussive brain injury
Acta Neuropathologica Communications · 2025
- BPS2025 - Dendritic targeting of spinocerebellar ataxia-related ion channels in cerebellar Purkinje neurons requires a microtubule-stabilizing protein
Biophysical Journal · 2025
- BPS2025 - Dendritic targeting of spinocerebellar ataxia-related ion channels in cerebellar Purkinje neurons requires a microtubule stabilizing protein
Biophysical Journal · 2025
- Marcks overexpression in retinal ganglion cells promotes optic nerve regeneration
Cell Death and Disease · 2024
- Discovering functional interactions among schizophrenia-risk genes by combining behavioral genetics with cell biology
Neuroscience & Biobehavioral Reviews · 2024
- A cytoskeleton-membrane interaction conserved in fast-spiking neurons controls movement, emotion, and memory
Molecular Psychiatry · 2023
- Immediate induction of varicosities by transverse compression but not uniaxial stretch in axon mechanosensation
Acta Neuropathologica Communications · 2022
- The Mechanical Microenvironment Regulates Axon Diameters Visualized by Cryo-Electron Tomography
Cells · 2022
- Rapid and Reversible Development of Axonal Varicosities: A New Form of Neural Plasticity
Frontiers in Molecular Neuroscience · 2021
- Decision letter: Kv3.3 subunits control presynaptic action potential waveform and neurotransmitter release at a central excitatory synapse
2021
- Function and Mechanism of Myelin Regulation in Alcohol Abuse and Alcoholism
BioEssays · 2019
- Region-specific interneuron demyelination and heightened anxiety-like behavior induced by adolescent binge alcohol treatment
Acta Neuropathologica Communications · 2019
- Copper chelation and autoimmunity differentially impact myelin in the hippocampal-prefrontal circuit
Journal of Neuroimmunology · 2019
- Regulation of Central Nervous System Myelination in Higher Brain Functions
Neural Plasticity · 2018
- Acta Neuropathologica Communications×3
- Frontiers in Molecular Neuroscience×3
- Biophysical Journal×2
- Neural Plasticity×1
- Mucosal Immunology×1
- Yang Yang
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Theodore Cummins
Biochemistry, Genetics and Molecular Biology · Indiana University
- Muriel Eaton
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Andy Hudmon
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Chunhua Yuan
Biochemistry, Genetics and Molecular Biology · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
Claim or correct this profile