Theodore Cummins
Biochemistry, Genetics and Molecular Biology · Indiana University
Publications
236
Citations
16,340
Est. group size
—
Recurring co-author estimate
Active years
36
Publishing since 1991
Theodore Cummins studies voltage-gated sodium channels—proteins in cell membranes that generate the electrical signals used by nerve and muscle cells. His work examines how specific channel types (such as Nav1.6, Nav1.7, and Nav1.8) contribute to pain, epilepsy, and neuronal excitability, and explores ways to target them for treatment, including gene-therapy approaches and natural toxins like scorpion venom.
Publication activity peaked around 2018-2020 and has slowed in recent years, averaging roughly four papers per year over the last five years.
Generated by claude-opus-4-8 from public bibliographic data · Jul 11, 2026
- An approach to targeting Nav1.7 for pain sensations
Journal of Clinical Investigation · 2025
- Contusive spinal cord injury causes Nav1.8 dysfunction to upregulate small sensory neuron excitability
The Journal of Physiology · 2025
- Differential Regulation of Nav1.1 and SCN1A Disease Mutant Sodium Current Properties by Fibroblast Growth Factor Homologous Factors
Cells · 2025
- Peripherally targeted analgesia via AAV-mediated sensory neuron–specific inhibition of multiple pronociceptive sodium channels
Journal of Clinical Investigation · 2024
- Molecular determinants of resurgent sodium currents mediated by Navβ4 peptide and A-type FHFs
Frontiers in Molecular Neuroscience · 2024
- Structural and Functional Characterization of a Novel Scorpion Toxin that Inhibits NaV1.8 via Interactions With the DI Voltage Sensor and DII Pore Module
Frontiers in Pharmacology · 2022
- Whole exome sequencing and co‐expression analysis identify an <i>SCN1A</i> variant that modifies pathogenicity in a family with genetic epilepsy and febrile seizures plus
Epilepsia · 2022
- CaMKII Inhibition Attenuates Distinct Gain-of-Function Effects Produced by Mutant Nav1.6 Channels and Reduces Neuronal Excitability
Cells · 2022
- A-type FHFs mediate resurgent currents through TTX-resistant voltage-gated sodium channels
bioRxiv (Cold Spring Harbor Laboratory) · 2022
- Author response: A-type FHFs mediate resurgent currents through TTX-resistant voltage-gated sodium channels
2022
- Decision letter: SUMOylation of NaV1.2 channels regulates the velocity of backpropagating action potentials in cortical pyramidal neurons
2022
- Distinctive Properties and Powerful Neuromodulation of Nav1.6 Sodium Channels Regulates Neuronal Excitability
Cells · 2021
- Identification and Characterization of Novel Proteins from Arizona Bark Scorpion Venom That Inhibit Nav1.8, a Voltage-Gated Sodium Channel Regulator of Pain Signaling
Toxins · 2021
- Identification and characterization of novel proteins from Arizona bark scorpion venom that inhibit Nav1.8, a voltage-gated sodium channel regulator of pain signaling
bioRxiv (Cold Spring Harbor Laboratory) · 2021
- Peripherally targeted analgesia via AAV-mediated sensory neuron-specific inhibition of multiple pronociceptive sodium channels in rat
bioRxiv (Cold Spring Harbor Laboratory) · 2021
- PMC×11
- bioRxiv (Cold Spring Harbor Laboratory)×7
- Figshare×6
- Stem Cell Reports×4
- Investigative Ophthalmology & Visual Science×4
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 11, 2026.
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