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Brian D. Fries

Biochemistry, Genetics and Molecular Biology · The Ohio State University

OpenAlex
Mid career · publishing since 2015Rising activity
Metabolomics and Mass Spectrometry StudiesAdvanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and ApplicationsRNA modifications and cancerCancer, Lipids, and Metabolism

Publications

16

Citations

85

Est. group size

~7

Recurring co-author estimate

Active years

11

Publishing since 2015

Research summary
AI-generated

Brian D. Fries works on mass spectrometry-based methods to study cancer biology, focusing on proteins, lipids, and their modifications in colorectal cancer models. Much of the recent work examines 3D 'spheroid' cell culture models to track how proteins, lipid metabolism, and cell signaling change during tumor growth and after blocking fatty acid synthesis. This research aims to understand molecular differences between cancer cells that spread (metastasize) and those that do not.

Mass spectrometry-based proteomicsLipidomics and lipid metabolism in cancerColorectal cancer cell biology3D spheroid cancer modelsHistone and protein modification analysis

Publication output was sparse and irregular from 2017-2022 but increased sharply from 2023 onward, with a notable surge in 2025.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 2.6/year recently
17182019: 1 publication19202021: 1 publication21222023: 4 publications232024: 1 publication242025: 8 publications82526
Recent publications
Publishes in
  • Journal of Proteome Research×3
  • ChemRxiv×2
  • PROTEOMICS×1
  • International Journal of Molecular Sciences×1
  • Analytical Chemistry×1
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By research-topic overlap
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This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 19, 2026.

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