Ashton S. Holub
Agricultural and Biological Sciences · The Ohio State University
Publications
12
Citations
82
Est. group size
~2
Recurring co-author estimate
Active years
11
Publishing since 2016
Ashton S. Holub's recent work focuses on a protein module called the START domain, studying how it regulates plant transcription factors (proteins that control gene activity) and how mutations in similar domains relate to cancer. Earlier work in the group spanned genome-wide DNA methylation mapping, retina gene expression, and developmental genetics in copepods, indicating a broad background in molecular biology and genomics before narrowing toward transcriptional regulation and START domain structure-function studies.
Publication output has been low and irregular over the last decade, with several gap years followed by a modest, fairly steady trickle of one to two papers per year since 2022.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Somatic variants activating the RAS-MAPK pathway confer susceptibility to hippocampal sclerosis in drug-resistant epilepsy
bioRxiv (Cold Spring Harbor Laboratory) · 2026
- A cryptic START domain regulates deeply conserved transcription factors
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- START domains generate paralog-specific regulons from a single network architecture
Nature Communications · 2024
- START domains generate paralog-specific regulons from a single network architecture
bioRxiv (Cold Spring Harbor Laboratory) · 2024
- The START domain potentiates HD-ZIPIII transcriptional activity
The Plant Cell · 2023
- The START domain potentiates HD-ZIPIII transcriptional activity
bioRxiv (Cold Spring Harbor Laboratory) · 2022
- Mutation Spectra of the MRN (MRE11, RAD50, NBS1/NBN) Break Sensor in Cancer Cells
Cancers · 2020
- Identifying Cancer-Relevant Mutations in the DLC START Domain Using Evolutionary and Structure-Function Analyses
International Journal of Molecular Sciences · 2020
- Identifying Cancer-Relevant Mutations in the DLC START Domain using Evolutionary and Structure-Function Analyses
bioRxiv (Cold Spring Harbor Laboratory) · 2020
- Whole genome DNA methylation sequencing of the chicken retina, cornea and brain
Scientific Data · 2017
- RNA-seq analysis of the human retina
Investigative Ophthalmology & Visual Science · 2017
- Embryonic development and a quantitative model of programmed DNA elimination in Mesocyclops edax (S. A. Forbes, 1891) (Copepoda: Cyclopoida)
Journal of Crustacean Biology · 2016
- bioRxiv (Cold Spring Harbor Laboratory)×5
- The Plant Cell×1
- Cancers×1
- International Journal of Molecular Sciences×1
- Journal of Crustacean Biology×1
- Rajeev Ranjan
Agricultural and Biological Sciences · Purdue University West Lafayette
- Kranthi Varala
Agricultural and Biological Sciences · Purdue University West Lafayette
- Prativa Amom
Agricultural and Biological Sciences · The Ohio State University
- Jing Yuan
Agricultural and Biological Sciences · Purdue University West Lafayette
- Ricardo A. Chávez Montes
Agricultural and Biological Sciences · Indiana University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
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