Alexander J.R. Bishop
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
171
Citations
3,738
Est. group size
~7
Recurring co-author estimate
Active years
57
Publishing since 1969
Alexander J.R. Bishop's research focuses on the molecular mechanisms underlying cancer and DNA damage, including how proteins that repair broken DNA or regulate gene expression malfunction in diseases like ovarian cancer, lung cancer, and Ewing sarcoma (a bone cancer). His work also touches on rare inherited conditions such as Ataxia telangiectasia, examining how defective cellular transport and DNA repair contribute to disease. Overall, the lab studies how errors in DNA repair, gene regulation, and cell signaling drive cancer development and how these insights might inform treatment strategies.
Publication output has grown substantially over the last decade, rising from single digits in 2017-2020 to a peak of 36 in 2023, with continued high output in 2025.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Phase separation of the oncogenic fusion protein EWS::FLI1 is modulated by its DNA-binding domain
Proceedings of the National Academy of Sciences · 2025
- SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
Cancer Research · 2025
- Heterogeneous expression of immunotherapy response markers in non-small cell lung cancer with hyperactive NRF2 pathway: PD-L1 and beyond
Redox Biology · 2025
- Loss of CD98HC phosphorylation by ATM impairs antiporter trafficking and drives glutamate toxicity in Ataxia telangiectasia
Nature Communications · 2025
- Data from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
2025
- Table S1 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
2025
- Figure S8 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
2025
- Figure S11 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
2025
- Figure S9 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
2025
- Figure S2 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
2025
- Figure S1 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
2025
- Figure S7 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
2025
- Figure S12 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
2025
- Figure S10 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
2025
- Table S5 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
2025
- Innovation in Aging×9
- Cancer Research×8
- Nature×4
- Nucleic Acids Research×4
- bioRxiv (Cold Spring Harbor Laboratory)×4
- Hengyao Niu
Biochemistry, Genetics and Molecular Biology · Indiana University
- Hannah L. Klein
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Ruben C. Petreaca
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Chunhua Han
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Jiangchuan Shen
Biochemistry, Genetics and Molecular Biology · Indiana University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
Claim or correct this profile