Hengyao Niu
Biochemistry, Genetics and Molecular Biology · Indiana University
Publications
73
Citations
4,229
Est. group size
—
Recurring co-author estimate
Active years
26
Publishing since 2001
Hengyao Niu studies how cells detect and repair damage to their DNA, focusing on the molecular machines and enzymes involved in repairing double-strand breaks and coping with problems that arise when DNA is copied. Much of the work uses yeast as a model organism and biochemical/structural approaches to understand proteins like Rad5, Rad51, Rad52, Dna2, and topoisomerases, with connections to how faulty repair can contribute to cancer.
Publication activity has been fairly steady over the past decade, averaging a few papers per year with a recent modest uptick in 2025-2026.
Generated by claude-opus-4-8 from public bibliographic data · Jul 11, 2026
- A dual role of EZH2 in regulating A-to-I RNA editing and mRNA stability through ADAR
Nature Communications · 2026
- Abstract 515: Substrate selectivity and RPA-mediated regulation of Topoisomerase3-Rmi1 decatenation.
Cancer Research · 2026
- PARP1 regulates the genomic ribonucleotide processing activity of TOP1 to prevent the formation of toxic TOP1-DNA adducts and the associated mutations
bioRxiv (Cold Spring Harbor Laboratory) · 2026
- Yeast DNA Polymerase δ Proofreading Nuclease Suppresses Translesion Synthesis and Facilitates Recombination in DNA Lesion Bypass
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- ssDNA accessibility of Rad51 is regulated by orchestrating multiple RPA dynamics
Nature Communications · 2023
- Mechanistic Insights into the Multiple Activities of the Rad5 Family of Enzymes
Journal of Molecular Biology · 2022
- A PRC2-independent function for EZH2 in regulating rRNA 2′-O methylation and IRES-dependent translation
Nature Cell Biology · 2021
- Structural basis for the multi-activity factor Rad5 in replication stress tolerance
Nature Communications · 2021
- Structure of Rad5 provides insights into its role in tolerance to replication stress
Molecular & Cellular Oncology · 2021
- Rad52 Restrains Resection at DNA Double-Strand Break Ends in Yeast
Molecular Cell · 2019
- Apn2 resolves blocked 3′ ends and suppresses Top1-induced mutagenesis at genomic rNMP sites
Nature Structural & Molecular Biology · 2019
- DNA duplex recognition activates Exo1 nuclease activity
Journal of Biological Chemistry · 2019
- Guidelines for DNA recombination and repair studies: Mechanistic assays of DNA repair processes
Microbial Cell · 2019
- Phospho-dependent recruitment of the yeast NuA4 acetyltransferase complex by MRX at DNA breaks regulates RPA dynamics during resection
Proceedings of the National Academy of Sciences · 2018
- Nucleosome-like, Single-stranded DNA (ssDNA)-Histone Octamer Complexes and the Implication for DNA Double Strand Break Repair
Journal of Biological Chemistry · 2017
- bioRxiv (Cold Spring Harbor Laboratory)×5
- Figshare×5
- Nature Communications×4
- Nucleic Acids Research×3
- Science Advances×2
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 11, 2026.
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